dc.contributor.author |
Forster, R |
en |
dc.contributor.author |
Ng, D |
en |
dc.contributor.author |
Upton, A |
en |
dc.contributor.author |
Franklin, R |
en |
dc.contributor.author |
Thomas, Mark |
en |
dc.date.accessioned |
2017-08-17T02:21:52Z |
en |
dc.date.issued |
2017-06 |
en |
dc.identifier.citation |
Internal Medicine Journal 47(6):640-648 Jun 2017 |
en |
dc.identifier.issn |
1444-0903 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/35167 |
en |
dc.description.abstract |
Background The relentless emergence and spread of strains of Neisseria gonorrhoeae that are resistant to many antimicrobial agents has led to frequent changes in treatment guidelines, with a consequent risk that prescribers may not be aware of current guidelines. Aim To determine the proportion of patients with gonorrhoea who were treated with a regimen consistent with the New Zealand Sexual Health Society (NZSHS) guidelines. Methods We audited the treatment given to adult patients with laboratory-proven gonorrhoea in Auckland, New Zealand, during the first 6 months of 2015. Results Treatment compliant with the current NZSHS guidelines was administered in only 65% (458/706) episodes overall. Guideline-compliant treatment was much more likely to be prescribed for patients who presented to a sexual health clinic (89%) than for patients who presented to either a general practice or other community clinic (52%) or to a hospital (56%) (P < 0.0001). Overall, 52 of 706 (7%) episodes were not treated with any antimicrobial regimen by the service that diagnosed the patients’ gonorrhoea, 13 of 62 (21%) episodes in patients who presented to a hospital, 34 of 403 (8%) episodes in patients who presented to a general practice or other community clinic and 5 of 241 (2%) episodes in patients who presented to a sexual health clinic (P < 0.0001). Conclusion Low levels of compliance with treatment guidelines increase the risk that antibiotic-resistant strains of N. gonorrhoeae will spread within the Auckland region. Improved compliance with treatment guidelines, particularly in patients who present either to general practice or to hospitals, is necessary to maintain the efficacy of current treatment regimens. |
en |
dc.publisher |
Blackwell Publishing Inc. |
en |
dc.relation.ispartofseries |
Internal Medicine Journal |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Treatment of gonorrhoea in Auckland, New Zealand: marked variation in prescriber adherence to treatment guidelines |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1111/imj.13433 |
en |
pubs.issue |
6 |
en |
pubs.begin-page |
640 |
en |
pubs.volume |
47 |
en |
dc.rights.holder |
Copyright: Wiley |
en |
pubs.end-page |
648 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Article |
en |
pubs.elements-id |
631863 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Medical Sciences |
en |
pubs.org-id |
Molecular Medicine |
en |
pubs.record-created-at-source-date |
2017-08-17 |
en |
pubs.online-publication-date |
2017-06-04 |
en |