Natural and synthetic derivatives of discorhabdin C, a cytotoxic pigment from the New Zealand sponge Latrunculia cf. bocagei

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dc.contributor.author Copp, Brent en
dc.contributor.author Fulton, KF en
dc.contributor.author Perry, NB en
dc.contributor.author Blunt, JW en
dc.contributor.author Munro, MHG en
dc.date.accessioned 2017-10-23T23:38:37Z en
dc.date.issued 1994-12 en
dc.identifier.citation Journal of Organic Chemistry 59(26):8233-8238 Dec 1994 en
dc.identifier.issn 0022-3263 en
dc.identifier.uri http://hdl.handle.net/2292/36197 en
dc.description.abstract Modification of the spiro-cyclohexadienone skeleton of discorhabdin C (3) led to a series of derivatives 6–11. The biological properties of this series were evaluated in a wide range of screens for selective cytotoxicity, antifungal, and antimicrobial properties. The structure and biological properties of a further discorhabdin, discorhabdin E (5), from a New Zealand sponge Latrunculia cf. bocagei are also presented. en
dc.publisher American Chemical Society en
dc.relation.ispartofseries Journal of Organic Chemistry en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.title Natural and synthetic derivatives of discorhabdin C, a cytotoxic pigment from the New Zealand sponge Latrunculia cf. bocagei en
dc.type Journal Article en
dc.identifier.doi 10.1021/jo00105a047 en
pubs.issue 26 en
pubs.begin-page 8233 en
pubs.volume 59 en
dc.rights.holder Copyright: American Chemical Society en
pubs.end-page 8238 en
pubs.publication-status Published en
dc.rights.accessrights http://purl.org/eprint/accessRights/RestrictedAccess en
pubs.subtype Article en
pubs.elements-id 132710 en
pubs.org-id Science en
pubs.org-id Chemistry en
pubs.org-id Science Research en
pubs.org-id Maurice Wilkins Centre (2010-2014) en
dc.identifier.eissn 1520-6904 en
pubs.record-created-at-source-date 2017-10-24 en


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