dc.contributor.author |
Hamill, James |
en |
dc.contributor.author |
Rahiri, Jamie-Lee |
en |
dc.contributor.author |
Liley, A |
en |
dc.contributor.author |
Hill, Andrew |
en |
dc.date.accessioned |
2017-12-11T00:01:43Z |
en |
dc.date.issued |
2016 |
en |
dc.identifier.issn |
0939-7248 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/36713 |
en |
dc.description.abstract |
Introduction Systematic reviews report intraperitoneal local anesthetic (IPLA) effective in adults but until now no review has addressed IPLA in children. The objective of this review was to answer the question, does IPLA compared with control reduce pain after pediatric abdominal surgery. Materials and Methods Data sources: MEDLINE, EMBASE, Cochrane databases, trials registries, ProQuest, Web of Science, Google Scholar, and Open Gray.Independent duplicate searching for randomized controlled trials of IPLA versus no IPLA/placebo in children ≤ 18 years of age, reporting pain, or opioid use outcomes.Independent duplicate data extraction and quality assessment using standardized fields. Results The selection process uncovered three eligible published trials and one unpublished study, all in laparoscopy surgery. Qualitative synthesis suggested that IPLA may reduce pain scores, opioid use, time to first opioid, and the need for rescue analgesia, with no effect on hospital stay. Risk of bias was significant. Conclusions IPLA appears promising in pediatric surgery. The high absorptive capacity of the peritoneum and high peritoneal surface area to volume ratio in children presents a dose limitation. In comparison to adult surgery, IPLA has been understudied in pediatric surgery. |
en |
dc.format.medium |
Print-Electronic |
en |
dc.language |
eng |
en |
dc.publisher |
Thieme Publishing |
en |
dc.relation.ispartofseries |
European Journal of Pediatric Surgery |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
Abdomen |
en |
dc.subject |
Peritoneum |
en |
dc.subject |
Humans |
en |
dc.subject |
Pain, Postoperative |
en |
dc.subject |
Analgesics, Opioid |
en |
dc.subject |
Anesthetics, Local |
en |
dc.subject |
Pain Measurement |
en |
dc.subject |
Laparoscopy |
en |
dc.subject |
Anesthesia, Local |
en |
dc.subject |
Injections, Intraperitoneal |
en |
dc.subject |
Adolescent |
en |
dc.subject |
Adult |
en |
dc.subject |
Child |
en |
dc.subject |
Child, Preschool |
en |
dc.subject |
Randomized Controlled Trials as Topic |
en |
dc.title |
Intraperitoneal local anesthetic in pediatric surgery: A systematic review |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1055/s-0036-1582243 |
en |
pubs.issue |
6 |
en |
pubs.begin-page |
469 |
en |
pubs.volume |
26 |
en |
dc.rights.holder |
Copyright: Thieme Publishing |
en |
dc.identifier.pmid |
27105452 |
en |
pubs.end-page |
475 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Review |
en |
pubs.elements-id |
526935 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
School of Medicine |
en |
pubs.org-id |
South Auckland clinical school |
en |
pubs.org-id |
Surgery Department |
en |
dc.identifier.eissn |
1439-359X |
en |
pubs.record-created-at-source-date |
2017-12-11 |
en |
pubs.dimensions-id |
27105452 |
en |