Assessing the effect of kiwifruit extracts on the human gut microbiota

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dc.contributor.advisor Taylor, M en
dc.contributor.advisor Poppitt, S en Liu, Yao Chin en 2018-06-22T01:23:53Z en 2018 en
dc.identifier.uri en
dc.description Full text is available to authenticated members of The University of Auckland only. en
dc.description.abstract Kiwifruit is among the top horticultural exports of New Zealand, with an export revenue surpassing that of wine in 2016. Whole kiwifruit boasts proven health benefits such as enhancing gut comfort (bowel regularity) due to an abundance of micronutrients and bioactive components. Though dietary intervention using whole fruits has shown consistent improvements in gut health, studies using kiwifruit extracts have proven inconclusive. Furthermore, the effects of kiwifruit extract on the composition and structure of the human gut microbiota are unclear. This is an important consideration, as the gut microbiota plays a critical role in human digestion and overall health. This study aims to determine the effects of kiwifruit extracts on the bacterial and fungal composition of the human gut microbiota. I shall use the 16S rRNA and ITS2 to amplify bacterial and fungal sequences respectively. Following that, rarefied OTU tables will be made from the obtained sequences and be used to calculate alpha-diversity and beta-diversity metrics which in turn is used to create distance matrices. This information will be visualized through rarefaction curves, PCoA plots, and nMDS plots. Finally, the PERMANOVA statistical test will confirm the validity of the findings. Through clarifying the effects of kiwifruit extracts on the human gut microbiota composition, I hope the results from this study may incentivize commercial development of kiwifruit extracts alongside whole kiwifruit as another source of export revenue for New Zealand. en
dc.publisher ResearchSpace@Auckland en
dc.relation.ispartof Masters Thesis - University of Auckland en
dc.relation.isreferencedby UoA99265073907402091 en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights Restricted Item. Available to authenticated members of The University of Auckland. en
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dc.rights.uri en
dc.title Assessing the effect of kiwifruit extracts on the human gut microbiota en
dc.type Thesis en Biological Sciences en The University of Auckland en Masters en
dc.rights.holder Copyright: The author en
pubs.elements-id 745268 en
pubs.record-created-at-source-date 2018-06-22 en

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