Vessel orientation constrained quantitative susceptibility mapping (QSM) reconstruction

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dc.contributor.author Cetin, S en
dc.contributor.author Bilgic, B en
dc.contributor.author Fan, A en
dc.contributor.author Holdsworth, Samantha en
dc.contributor.author Unal, G en
dc.date.accessioned 2018-10-10T22:48:41Z en
dc.date.issued 2016-01-01 en
dc.identifier.citation Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 9902 LNCS: 467-474. 01 Jan 2016 en
dc.identifier.isbn 9783319467252 en
dc.identifier.issn 0302-9743 en
dc.identifier.uri http://hdl.handle.net/2292/40588 en
dc.description.abstract © Springer International Publishing AG 2016. QSM is used to estimate the underlying tissue magnetic susceptibility and oxygen saturation in veins. This paper presents vessel orientation as a new regularization term to improve the accuracy of l1 regularized QSM reconstruction in cerebral veins. For that purpose,the vessel tree is first extracted from an initial QSM reconstruction. In a second step,the vascular geometric prior is incorporated through an orthogonality constraint into the QSM reconstruction. Using a multi-orientation QSM acquisition as gold standard,we show that the QSM reconstruction obtained with the vessel anatomy prior provides up to 40% RMSE reduction relative to the baseline l1 regularizer approach. We also demonstrate in vivo OEF maps along venous veins based on segmentations from QSM. The utility of the proposed method is further supported by inclusion of a separate MRI venography scan to introduce more detailed vessel orientation information into the reconstruction,which provides significant improvement in vessel conspicuity. en
dc.relation.ispartofseries Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights his is a post-peer-review, pre-copyedit version of an article published in Lecture notes in Computer Science. The final authenticated version is available online at: http://dx.doi.org/10.1007/978-3-319-46726-9_54 en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.rights.uri https://www.springer.com/gb/open-access/authors-rights/self-archiving-policy/2124 en
dc.title Vessel orientation constrained quantitative susceptibility mapping (QSM) reconstruction en
dc.type Conference Item en
dc.identifier.doi 10.1007/978-3-319-46726-9_54 en
pubs.begin-page 467 en
pubs.volume 9902 LNCS en
dc.rights.holder Copyright: Springer en
pubs.end-page 474 en
pubs.publication-status Published en
dc.rights.accessrights http://purl.org/eprint/accessRights/OpenAccess en
pubs.elements-id 683315 en
pubs.org-id Medical and Health Sciences en
pubs.org-id Medical Sciences en
pubs.org-id Anatomy and Medical Imaging en
dc.identifier.eissn 1611-3349 en


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