dc.contributor.author |
McCambridge, Alana B |
en |
dc.contributor.author |
Stinear, James |
en |
dc.contributor.author |
Peek, Sarah |
en |
dc.contributor.author |
Byblow, Winston |
en |
dc.date.accessioned |
2018-10-11T03:12:55Z |
en |
dc.date.issued |
2017-09 |
en |
dc.identifier.issn |
1388-2457 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/40851 |
en |
dc.description.abstract |
Cervical propriospinal premotoneurons (PN) relay descending motor commands and integrate peripheral afferent feedback. Effects of anodal transcranial direct current stimulation (a-tDCS) on propriospinal excitability in the upper limbs are unknown.Healthy right-handed adults received a-tDCS or sham tDCS over primary motor cortex (M1) at 1mA (Experiment 1, n=18) or 2mA current intensity (Experiment 2, n=15). Propriospinal excitability was assessed by suppression of background electromyography (EMG) in extensor carpi radialis (ECR) from electrical stimulation of the superficial radial nerve during bilateral (Experiment 1 and 2) or unilateral (Experiment 2 only) activation of the left and/or right ECR. EMG suppression could be attributed to an early propriospinal component and late cortical component. Motor evoked potentials (MEP) were obtained as a manipulation check.Before tDCS, propriospinal-mediated cutaneous-induced suppression was present in each arm for early and late components. ECR MEP amplitude increased after 1mA, but not 2mA, a-tDCS. Neither 1mA nor 2mA a-tDCS modulated either component of ipsilateral or contralateral propriospinal excitability during bilateral or unilateral tasks.Propriospinal-mediated cutaneous-induced suppression was not modulated by a-tDCS in healthy adults.Reporting non-significant findings is paramount for the development of clinically-relevant tDCS protocols. |
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dc.format.medium |
Print-Electronic |
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dc.language |
eng |
en |
dc.relation.ispartofseries |
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology |
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dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
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dc.subject |
Motor Cortex |
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dc.subject |
Spinal Cord |
en |
dc.subject |
Motor Neurons |
en |
dc.subject |
Spinal Nerves |
en |
dc.subject |
Radial Nerve |
en |
dc.subject |
Humans |
en |
dc.subject |
Electromyography |
en |
dc.subject |
Double-Blind Method |
en |
dc.subject |
Evoked Potentials, Motor |
en |
dc.subject |
Adult |
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dc.subject |
Aged |
en |
dc.subject |
Middle Aged |
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dc.subject |
Female |
en |
dc.subject |
Male |
en |
dc.subject |
Young Adult |
en |
dc.subject |
Transcranial Direct Current Stimulation |
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dc.title |
Propriospinal cutaneous-induced EMG suppression is unaltered by anodal tDCS of healthy motor cortex. |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1016/j.clinph.2017.06.035 |
en |
pubs.issue |
9 |
en |
pubs.begin-page |
1608 |
en |
pubs.volume |
128 |
en |
dc.rights.holder |
Copyright: The author |
en |
dc.identifier.pmid |
28715712 |
en |
pubs.end-page |
1616 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Research Support, Non-U.S. Gov't |
en |
pubs.subtype |
Randomized Controlled Trial |
en |
pubs.subtype |
Journal Article |
en |
pubs.elements-id |
638878 |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Exercise Sciences |
en |
dc.identifier.eissn |
1872-8952 |
en |
pubs.record-created-at-source-date |
2017-07-18 |
en |
pubs.dimensions-id |
28715712 |
en |