Gene therapy-based modelling of neurodegenerative disorders: Huntington's disease

Young, Deborah

dc.contributor.author	Young, Deborah	en
dc.date.accessioned	2018-10-14T23:54:06Z	en
dc.date.issued	2016	en
dc.identifier.isbn	978-1-4939-3270-2	en
dc.identifier.uri	http://hdl.handle.net/2292/41452	en
dc.description.abstract	Huntington’s disease is a fatal neurodegenerative disease characterized by impairments in motor control, and cognitive and psychiatric disturbances. In this chapter, viral vector-mediated approaches used in modeling the key neuropathological features of the disease including the production of abnormal intracellular protein aggregates, neuronal dysfunction and degeneration and motor impairments in rodents are described.	en
dc.description.uri	https://catalogue.library.auckland.ac.nz/primo-explore/fulldisplay?docid=uoa_alma51287217430002091&context=L&vid=NEWUI	en
dc.publisher	Springer	en
dc.relation.ispartof	Gene Therapy for Neurological Disorders: Methods and Protocols	en
dc.relation.ispartofseries	Methods in Molecular Biology	en
dc.rights	Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.	en
dc.rights.uri	https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm	en
dc.rights.uri	https://www.springer.com/gp/open-access/authors-rights/self-archiving-policy/2124	en
dc.title	Gene therapy-based modelling of neurodegenerative disorders: Huntington's disease	en
dc.type	Book Item	en
dc.identifier.doi	10.1007/978-1-4939-3271-9_27	en
pubs.begin-page	383	en
pubs.volume	1382	en
dc.rights.holder	Copyright: Springer Science+Business Media	en
dc.identifier.pmid	26611601	en
pubs.author-url	https://books.google.co.nz/books?id=SoImtAEACAAJ	en
pubs.end-page	395	en
pubs.place-of-publication	New York	en
dc.rights.accessrights	http://purl.org/eprint/accessRights/OpenAccess	en
pubs.elements-id	464324	en
pubs.org-id	Medical and Health Sciences	en
pubs.org-id	Medical Sciences	en
pubs.org-id	Pharmacology	en
pubs.number	27	en
pubs.record-created-at-source-date	2014-11-28	en
pubs.dimensions-id	26611601	en