Abstract:
Atropine eye drops are currently the most effective treatment for progressing myopia, however, the site of atropine’s anti-myopia action is still unknown. It is known that optical defocus produces sign dependent changes in the electrical activity of the retina— hyperopic defocus is associated with reduced retinal responses whereas, myopic defocus causes an increase. Recently, we investigated the effects of 0.1% atropine on inner and outer retinal electrophysiological responses to short-term imposed defocus. This talk will highlight the findings from this study, which suggest that myopia control with atropine might be based on a retinal site of atropine’s action.