The Healthy Mums and Babies (HUMBA) randomised demonstration trial protocol (poster);

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dc.contributor.author Gafa, CK en
dc.contributor.author Li, Minglan en
dc.contributor.author Taylor, Rennae en
dc.contributor.author Thompson, John en
dc.contributor.author McKinlay, Christopher en
dc.contributor.author Crowther, Caroline en
dc.contributor.author McCowan, Lesley en
dc.coverage.spatial Barcelona, Spain en
dc.date.accessioned 2018-10-17T02:43:27Z en
dc.date.issued 2017-03-08 en
dc.identifier.uri http://hdl.handle.net/2292/42507 en
dc.description.abstract The Healthy Mums and Babies (HUMBA) trial was developed in response to an external review of maternity care in South Auckland, New Zealand. The review highlighted the contribution of obesity to the high perinatal mortality rate in the region especially among Pacific women. Obesity and excessive gestational weight gain increase risks of numerous pregnancy complications for the mother and the offspring as well as the risk of long term health problems for both. HUMBA is a two by two factorial randomised controlled demonstration trial, aiming to reduce excessive gestational weight gain in the mother, optimise infant birthweight and improve maternal glucose metabolism. The study will recruit 220 women with BMI≥30 and singleton pregnancy at 120-176 weeks’ gestation. Women with diabetes, previous bariatric surgery, taking probiotics or tablets affecting appetite and glucose metabolism will be excluded. Consenting participants are randomised via a web-based protocol, randomize.net to receive 1) a nutritional intervention or routine care, and 2) either an oral probiotic or placebo capsule. Nutritional intervention includes four face-to-face visits provided by community health workers trained in pregnancy nutrition, and supporting text messages. Participants with routine care will receive best practice pregnancy nutrition pamphlets from the New Zealand Ministry of Health. Probiotic capsules contains Lactobacillus rhamnosus GG and Bifidobacterium lactis BB12, 7x109 colony-forming units per capsule. Probiotic and placebo capsules are prescribed one per day from recruitment until birth in a double blinded fashion. One hundred and ninety women are recruited to date. Data on recruitment and participant demographics will be presented. en
dc.relation.ispartof Diabetes in Pregnancy 2017, The 9th International Symposium of Diabetes, Hypertension Metabolic Syndrome and Pregnancy en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.title The Healthy Mums and Babies (HUMBA) randomised demonstration trial protocol (poster); en
dc.type Conference Poster en
dc.rights.holder Copyright: The author en
dc.rights.accessrights http://purl.org/eprint/accessRights/RestrictedAccess en
pubs.elements-id 692811 en
pubs.org-id Liggins Institute en
pubs.org-id LiFePATH en
pubs.org-id Medical and Health Sciences en
pubs.org-id School of Medicine en
pubs.org-id Obstetrics and Gynaecology en
pubs.org-id Paediatrics Child & Youth Hlth en
pubs.record-created-at-source-date 2017-11-03 en


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