Quantifying the incidence and burden of herpes zoster in New Zealand general practice: a retrospective cohort study using a natural language processing software inference algorithm.

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dc.contributor.author Turner, Nicola en
dc.contributor.author MacRae, Jayden en
dc.contributor.author Nowlan, Mary en
dc.contributor.author McBain, Lynn en
dc.contributor.author Stubbe, Maria H en
dc.contributor.author Dowell, Anthony en
dc.date.accessioned 2018-10-17T02:45:17Z en
dc.date.issued 2018-05-31 en
dc.identifier.issn 2044-6055 en
dc.identifier.uri http://hdl.handle.net/2292/42515 en
dc.description.abstract OBJECTIVE:To investigate the incidence of primary care presentations for herpes zoster (zoster) in a representative New Zealand population and to evaluate the utilisation of primary healthcare services following zoster diagnosis. DESIGN:A cross-sectional retrospective cohort study used a natural language processing software inference algorithm to identify general practice consultations for zoster by interrogating 22 million electronic medical record (EMR) transactions routinely recorded from January 2005 to December 2015. Data linking enabled analysis of the demographics of each case. The frequency of doctor visits was assessed prior to and after the first consultation diagnosing zoster to determine health service utilisation. SETTING:General practice, using EMRs from two primary health organisations located in the lower North Island, New Zealand. PARTICIPANTS:Thirty-nine general practices consented interrogation of their EMRs to access deidentified records for all enrolled patients. Out-of-hours and practice nurse consultations were excluded. MAIN OUTCOME MEASURES:The incidence of first and repeated zoster-related visits to the doctor across all age groups and associated patient demographics. To determine whether zoster affects workload in general practice. RESULTS:Overall, for 6 189 019 doctor consultations, the incidence of zoster was 48.6 per 10 000 patient-years (95% CI 47.6 to 49.6). Incidence increased from the age of 50 years to a peak rate of 128 per 10 000 in the age group of 80-90 years and was significantly higher in females than males (p<0.001). Over this 11-year period, incidence increased gradually, notably in those aged 80-85 years. Only 19% of patients had one or more follow-up zoster consultations within 12 months of a zoster index consultation. The frequency of consultations, for any reason, did not change between periods before and after the diagnosis. CONCLUSIONS:Zoster consultations in general practice are rare, and the burden of these cases on overall general practice caseload is low. en
dc.format.medium Electronic en
dc.language eng en
dc.relation.ispartofseries BMJ open en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. Details obtained from http://www.sherpa.ac.uk/romeo/issn/2044-6055/ en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/ en
dc.subject Humans en
dc.subject Herpesvirus 3, Human en
dc.subject Herpes Zoster en
dc.subject Incidence en
dc.subject Retrospective Studies en
dc.subject Cross-Sectional Studies en
dc.subject Age Factors en
dc.subject Sex Factors en
dc.subject Algorithms en
dc.subject Cost of Illness en
dc.subject Natural Language Processing en
dc.subject Adolescent en
dc.subject Adult en
dc.subject Aged en
dc.subject Aged, 80 and over en
dc.subject Middle Aged en
dc.subject Workload en
dc.subject New Zealand en
dc.subject Female en
dc.subject Male en
dc.subject Young Adult en
dc.subject General Practice en
dc.title Quantifying the incidence and burden of herpes zoster in New Zealand general practice: a retrospective cohort study using a natural language processing software inference algorithm. en
dc.type Journal Article en
dc.identifier.doi 10.1136/bmjopen-2017-021241 en
pubs.issue 5 en
pubs.begin-page e021241 en
pubs.volume 8 en
dc.rights.holder Copyright: The authors en
pubs.publication-status Published en
dc.rights.accessrights http://purl.org/eprint/accessRights/OpenAccess en
pubs.subtype Research Support, Non-U.S. Gov't en
pubs.subtype research-article en
pubs.subtype Journal Article en
pubs.elements-id 744300 en
dc.identifier.eissn 2044-6055 en
pubs.record-created-at-source-date 2018-06-03 en
pubs.dimensions-id 29858420 en

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http://creativecommons.org/licenses/by-nc/4.0/ Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc/4.0/


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