dc.contributor.author |
Holford, Nicholas |
en |
dc.date.accessioned |
2018-10-18T00:31:53Z |
en |
dc.date.issued |
2015-01 |
en |
dc.identifier.issn |
0306-5251 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/42785 |
en |
dc.description.abstract |
Clinical pharmacology is concerned with understanding how to use medicines to treat disease. Pharmacokinetics and pharmacodynamics have provided powerful methodologies for describing the time course of concentration and effect in individuals and in populations. This population approach may also be applied to describing the progression of disease and the action of drugs to change disease progress. Quantitative models for symptomatic and disease-modifying effects of drugs are valuable not only for describing drugs and diseases but also for identifying criteria to distinguish between types of drug actions, with implications for regulatory decisions and long-term patient care. |
en |
dc.format.medium |
Print |
en |
dc.language |
eng |
en |
dc.relation.ispartofseries |
British journal of clinical pharmacology |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
Humans |
en |
dc.subject |
Disease Progression |
en |
dc.subject |
Drug Therapy |
en |
dc.subject |
Pharmacology, Clinical |
en |
dc.subject |
Models, Biological |
en |
dc.title |
Clinical pharmacology = disease progression + drug action. |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1111/bcp.12170 |
en |
pubs.issue |
1 |
en |
pubs.begin-page |
18 |
en |
pubs.volume |
79 |
en |
dc.rights.holder |
Copyright: The author |
en |
dc.identifier.pmid |
23713816 |
en |
pubs.end-page |
27 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
review-article |
en |
pubs.subtype |
Review |
en |
pubs.subtype |
Journal Article |
en |
pubs.elements-id |
48854 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Medical Sciences |
en |
pubs.org-id |
Pharmacology |
en |
dc.identifier.eissn |
1365-2125 |
en |
pubs.record-created-at-source-date |
2014-12-22 |
en |
pubs.dimensions-id |
23713816 |
en |