The sex of the foetus affects maternal blood glucose concentrations in overweight and obese pregnant women.

Show simple item record Seneviratne, Sumudu N en Behrensdorf Derraik, Jose en Jiang, Yannan en McCowan, Lesley en Gusso, Silmara en Cutfield, Wayne en Hofman, Paul en 2018-11-01T20:27:09Z en 2017-07 en
dc.identifier.issn 0144-3615 en
dc.identifier.uri en
dc.description.abstract There is increasing evidence that the sex of the foetus may alter the maternal metabolic milieu during pregnancy. Following a randomized controlled trial of exercise in overweight and obese pregnant women, we assessed whether the sex of the foetus was associated with changes in maternal metabolism. Data were analysed on 74 randomized participants who completed the trial, including 38 mothers carrying males and 36 mothers carrying females. At 19 weeks of gestation, mothers carrying boys had higher blood glucose concentrations than those carrying girls (5.4 vs 4.9 mmol/l; p = .046). At 36 weeks of gestation, differences were more marked, with blood glucose concentrations 15% higher in mothers carrying females (5.7 vs 5.0 mmol/l; p = .004). In addition, mothers carrying girls had higher concentrations of hs-CRP across pregnancy (5.0 vs 3.6 mg/l; p = .029). Our findings provide further evidence that the sex of the foetus appears to influence maternal metabolism. en
dc.format.medium Print-Electronic en
dc.language eng en
dc.relation.ispartofseries Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri en
dc.subject Humans en
dc.subject Pregnancy Complications en
dc.subject Obesity en
dc.subject Blood Glucose en
dc.subject Pregnancy en
dc.subject Sex Characteristics en
dc.subject Female en
dc.subject Male en
dc.title The sex of the foetus affects maternal blood glucose concentrations in overweight and obese pregnant women. en
dc.type Journal Article en
dc.identifier.doi 10.1080/01443615.2016.1256970 en
pubs.issue 5 en
pubs.begin-page 667 en
pubs.volume 37 en
dc.rights.holder Copyright: The author en
dc.identifier.pmid 28019134 en
pubs.end-page 669 en
pubs.publication-status Published en
dc.rights.accessrights en
pubs.subtype Randomized Controlled Trial en
pubs.subtype Journal Article en
pubs.elements-id 605445 en Liggins Institute en Medical and Health Sciences en School of Medicine en Obstetrics and Gynaecology en Paediatrics Child & Youth Hlth en Science en Exercise Sciences en Statistics en
dc.identifier.eissn 1364-6893 en
pubs.record-created-at-source-date 2016-12-27 en
pubs.dimensions-id 28019134 en

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