Abstract:
The Physiome Project, which aims to use anatomically and biophysically based modelling as a basis for physiological understanding, is gaining momentum in several areas. The cardiac physiome project-the Cardiome Project-involving a number of research groups around the world, is an attempt to provide an integrated model of the heart, incorporating electrical activation, mechanical contraction, energy supply and utilisation, cell signalling and many other biochemical processes. This talk describes current progress on the following aspects of the cardiome project: database developments, model developments and visualisation