High content screening applications in a multi-user, multi-disciplinary biomedical imaging research unit

Abstract

High content screening and image analysis is an essential tool in hypothesis-driven research today. Through the use of advanced imaging systems such as the ImageXpress Micro XLS (Molecular Devices) and VSlide scanner (MetaSystems) in conjunction with image analysis software MetaXpress and data management solution MDCStore (Molecular Devices), we have established a virtual environment where users can remote in from anywhere in the world and conduct analysis tailored to their unique experiments, with speed and accuracy. Examples of data obtained from cell-based experiments in micro-well plates or chamber slides through to multi-core tissue microarrays will be presented from our multi-user facility at the Biomedical Imaging Research Unit at the University of Auckland. This presentation will highlight the application of these approaches to a diverse range of study designs.