dc.contributor.author |
Holdsworth, Samantha |
en |
dc.contributor.author |
Yeom, KW |
en |
dc.contributor.author |
Antonucci, MU |
en |
dc.contributor.author |
Andre, JB |
en |
dc.contributor.author |
Rosenberg, J |
en |
dc.contributor.author |
Aksoy, M |
en |
dc.contributor.author |
Straka, M |
en |
dc.contributor.author |
Fischbein, NJ |
en |
dc.contributor.author |
Bammer, R |
en |
dc.contributor.author |
Moseley, ME |
en |
dc.contributor.author |
Zaharchuk, G |
en |
dc.contributor.author |
Skare, S |
en |
dc.date.accessioned |
2018-11-13T23:08:05Z |
en |
dc.date.issued |
2014-07 |
en |
dc.identifier.citation |
American Journal of Neuroradiology 35(7):1293-1302 Jul 2014 |
en |
dc.identifier.issn |
0195-6108 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/44205 |
en |
dc.description.abstract |
Parallel imaging facilitates the acquisition of echo-planar images with a reduced TE, enabling the incorporation of an additional image at a later TE. Here we investigated the use of a parallel imaging-enhanced dual-echo EPI sequence to improve lesion conspicuity in diffusion-weighted imaging.Parallel imaging-enhanced dual-echo DWI data were acquired in 50 consecutive patients suspected of stroke at 1.5T. The dual-echo acquisition included 2 EPI for 1 diffusion-preparation period (echo 1 [TE = 48 ms] and echo 2 [TE = 105 ms]). Three neuroradiologists independently reviewed the 2 echoes by using the routine DWI of our institution as a reference. Images were graded on lesion conspicuity, diagnostic confidence, and image quality. The apparent diffusion coefficient map from echo 1 was used to validate the presence of acute infarction. Relaxivity maps calculated from the 2 echoes were evaluated for potential complementary information.Echo 1 and 2 DWIs were rated as better than the reference DWI. While echo 1 had better image quality overall, echo 2 was unanimously favored over both echo 1 and the reference DWI for its high sensitivity in detecting acute infarcts.Parallel imaging-enhanced dual-echo diffusion-weighted EPI is a useful method for evaluating lesions with reduced diffusivity. The long TE of echo 2 produced DWIs that exhibited superior lesion conspicuity compared with images acquired at a shorter TE. Echo 1 provided higher SNR ADC maps for specificity to acute infarction. The relaxivity maps may serve to complement information regarding blood products and mineralization. |
en |
dc.format.medium |
Print-Electronic |
en |
dc.language |
eng |
en |
dc.relation.ispartofseries |
AJNR. American journal of neuroradiology |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.rights.uri |
http://www.ajnr.org/page/content/Information-for-Authors#nih |
en |
dc.subject |
Brain |
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dc.subject |
Humans |
en |
dc.subject |
Acute Disease |
en |
dc.subject |
Image Interpretation, Computer-Assisted |
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dc.subject |
Observer Variation |
en |
dc.subject |
Diffusion Magnetic Resonance Imaging |
en |
dc.subject |
Echo-Planar Imaging |
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dc.subject |
Image Enhancement |
en |
dc.subject |
Sensitivity and Specificity |
en |
dc.subject |
Reproducibility of Results |
en |
dc.subject |
Adult |
en |
dc.subject |
Aged |
en |
dc.subject |
Middle Aged |
en |
dc.subject |
Female |
en |
dc.subject |
Male |
en |
dc.subject |
Stroke |
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dc.subject |
Multimodal Imaging |
en |
dc.title |
Diffusion-weighted imaging with dual-echo echo-planar imaging for better sensitivity to acute stroke. |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.3174/ajnr.a3921 |
en |
pubs.issue |
7 |
en |
pubs.begin-page |
1293 |
en |
pubs.volume |
35 |
en |
dc.rights.holder |
Copyright: American Journal of Neuroradiology |
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dc.identifier.pmid |
24763417 |
en |
pubs.end-page |
1302 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
Research Support, Non-U.S. Gov't |
en |
pubs.subtype |
research-article |
en |
pubs.subtype |
Journal Article |
en |
pubs.subtype |
Research Support, N.I.H., Extramural |
en |
pubs.elements-id |
683323 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Medical Sciences |
en |
pubs.org-id |
Anatomy and Medical Imaging |
en |
dc.identifier.eissn |
1936-959X |
en |
pubs.record-created-at-source-date |
2014-07-16 |
en |
pubs.dimensions-id |
24763417 |
en |