Prevalence of metabolic syndrome and metabolic syndrome components in young adults: A pooled analysis.

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Show simple item record Nolan, Paul en Carrick-Ranson, Graeme en Stinear, James en Reading, Stacey en Dalleck, Lance C en 2018-11-14T02:57:06Z en 2017-09 en
dc.identifier.citation Preventive Medicine Reports 7:211-215 Sep 2017 en
dc.identifier.issn 2211-3355 en
dc.identifier.uri en
dc.description.abstract Metabolic syndrome (MetSyn) represents a clustering of different metabolic abnormalities. MetSyn prevalence is present in approximately 25% of all adults with increased prevalence in advanced ages. The presence of one component of MetSyn increases the risk of developing MetSyn later in life and likely represents a high lifetime burden of cardiovascular disease risk. Therefore we pooled data from multiple studies to establish the prevalence of MetSyn and MetSyn component prevalence across a broad range of ethnicities. PubMed, SCOPUS and Medline databases were searched to find papers presenting MetSyn and MetSyn component data for 18-30 year olds who were apparently healthy, free of disease, and MetSyn was assessed using either the harmonized, National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATPIII), American Heart Association/National Heart, Blood and Lung Institute (AHA/NHBLI), or International Diabetes Federation (IDF) definitions of MetSyn. After reviewing returned articles, 26,609 participants' data from 34 studies were included in the analysis and the data were pooled. MetSyn was present in 4.8-7% of young adults. Atherogenic dyslipidaemia defined as low high density lipoprotein (HDL) cholesterol was the most prevalent MetSyn component (26.9-41.2%), followed by elevated blood pressure (16.6-26.6%), abdominal obesity (6.8-23.6%), atherogenic dyslipidaemia defined as raised triglycerides (8.6-15.6%), and raised fasting glucose (2.8-15.4%). These findings highlight that MetSyn is prevalent in young adults. Establishing the reason why low HDL is the most prevalent component may represent an important step in promoting primary prevention of MetSyn and reducing the incidence of subsequent clinical disease. en
dc.format.medium Electronic-eCollection en
dc.language eng en
dc.relation.ispartofseries Preventive Medicine Reports en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri en
dc.rights.uri en
dc.title Prevalence of metabolic syndrome and metabolic syndrome components in young adults: A pooled analysis. en
dc.type Journal Article en
dc.identifier.doi 10.1016/j.pmedr.2017.07.004 en
pubs.begin-page 211 en
pubs.volume 7 en
dc.rights.holder Copyright: The authors en
dc.identifier.pmid 28794957 en
pubs.end-page 215 en
pubs.publication-status Published en
dc.rights.accessrights en
pubs.subtype research-article en
pubs.subtype Journal Article en
pubs.elements-id 646023 en Science en Exercise Sciences en
dc.identifier.eissn 2211-3355 en
pubs.record-created-at-source-date 2017-08-11 en
pubs.dimensions-id 28794957 en

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