Antibiotic treatment of women with uncomplicated cystitis before and after allowing pharmacist-supply of trimethoprim.

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dc.contributor.author Gauld, Natalie en
dc.contributor.author Zeng, Sui en
dc.contributor.author Ikram, Rosemary B en
dc.contributor.author Thomas, Mark en
dc.contributor.author Buetow, Stephen en
dc.date.accessioned 2018-11-21T22:58:19Z en
dc.date.issued 2017-02 en
dc.identifier.issn 2210-7703 en
dc.identifier.uri http://hdl.handle.net/2292/44548 en
dc.description.abstract Background In 2012, New Zealand reclassified trimethoprim to allow specially trained pharmacists to supply it without a prescription to women with symptoms suggesting uncomplicated cystitis, under strict criteria for supply. Objective To assess how this policy change allowing pharmacist supply of trimethoprim affected overall antibiotic supply. Setting Randomly selected community pharmacies throughout New Zealand. Methods Data were collected in pharmacies before the implementation ('baseline') and 1 year later ('post-implementation'). Pharmacy staff recorded prescription and nonprescription supplies for treatment or prevention of suspected urinary tract infections. Women with a prescription for treatment or prevention of presumed urinary tract infection or purchasing a non-prescription medicine for this purpose were invited to self-complete a questionnaire. National prescribing data were extracted for trimethoprim, nitrofurantoin and norfloxacin. Main outcome measure Antibiotic use in women with UTIs from dispensed prescriptions (baseline and post-implementation) and pharmacist-supplied trimethoprim (post-implementation), particularly focusing on women aged 16-65 years with an antibiotic for presumed cystitis without complicating features. Results Baseline data were provided by 139 pharmacies, 120 of which provided post-implementation data. In women with presumed cystitis without complicating features, prescriptions before and after the implementation were primarily for trimethoprim. Overall antibiotic use, and use of second-line agents did not increase post-implementation. Pharmacist-supplies of trimethoprim were modest nearly 1 year after the service started. Conclusion Supply of trimethoprim by specially trained pharmacists working within strict criteria for supply appeared to have little overall effect on antibiotic use. Further research on patient outcomes, resistance and changes over time is recommended. en
dc.format.medium Print-Electronic en
dc.language eng en
dc.relation.ispartofseries International journal of clinical pharmacy en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.subject Humans en
dc.subject Cystitis en
dc.subject Trimethoprim en
dc.subject Anti-Infective Agents, Urinary en
dc.subject Anti-Bacterial Agents en
dc.subject Treatment Outcome en
dc.subject Pilot Projects en
dc.subject Professional Role en
dc.subject Pharmacists en
dc.subject Female en
dc.subject Surveys and Questionnaires en
dc.title Antibiotic treatment of women with uncomplicated cystitis before and after allowing pharmacist-supply of trimethoprim. en
dc.type Journal Article en
dc.identifier.doi 10.1007/s11096-016-0415-1 en
pubs.issue 1 en
pubs.begin-page 165 en
pubs.volume 39 en
dc.rights.holder Copyright: The author en
dc.identifier.pmid 28012119 en
pubs.end-page 172 en
pubs.publication-status Published en
dc.rights.accessrights http://purl.org/eprint/accessRights/RestrictedAccess en
pubs.subtype Comparative Study en
pubs.subtype Journal Article en
pubs.subtype Observational Study en
pubs.elements-id 605496 en
pubs.org-id Medical and Health Sciences en
pubs.org-id Medical Sciences en
pubs.org-id Molecular Medicine en
pubs.org-id Population Health en
pubs.org-id Gen.Practice& Primary Hlthcare en
dc.identifier.eissn 2210-7711 en
pubs.record-created-at-source-date 2016-12-24 en
pubs.dimensions-id 28012119 en


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