dc.contributor.author |
Holdsworth, Samantha |
en |
dc.contributor.author |
Macpherson, Sarah J |
en |
dc.contributor.author |
Yeom, Kristen W |
en |
dc.contributor.author |
Wintermark, Max |
en |
dc.contributor.author |
Zaharchuk, Greg |
en |
dc.date.accessioned |
2018-11-28T21:37:35Z |
en |
dc.date.issued |
2018-02 |
en |
dc.identifier.issn |
0361-803X |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/44660 |
en |
dc.description.abstract |
OBJECTIVE:New MRI sequences based on rapid radial acquisition have reduced gradient noise. The purpose of this study was to compare Silent T1-weighted and unenhanced MR angiography (MRA) against conventional sequences in a clinical population. MATERIALS AND METHODS:The study cohort consisted of 40 patients with suspected brain metastases (median age, 60 years; range, 23-91 years) who underwent T1-weighted contrast-enhanced MRI and 51 patients with suspected vascular lesions or cerebral ischemia (median age, 60 years; range, 16-94 years) who underwent unenhanced intracranial MRA. Three neuroradiologists reviewed the images blindly and rated several measures of image quality on a 5-point Likert scale. Reviewers recorded the number of enhancing lesions and whether Silent images were better than, worse than, or equivalent to conventional images. RESULTS:For T1-weighted MR images, ratings were slightly lower for Silent versus conventional images, except for diagnostic confidence. Although more lesions were detected on conventional images, this difference was not statistically significant; agreement was seen in 88% of cases. In 48% of cases, T1-weighted scans were deemed equivalent, but when a preference existed, it was usually for conventional images (38% vs 14%). Conventional MRA images were rated higher on all image quality metrics and were strongly preferred (reviewers preferred conventional images in 69% of cases, rated the images as equivalent in 27% of cases, and preferred Silent images in 4% of cases). In some cases, artifacts on Silent images caused reduced vessel caliber, vessel irregularities, and even absent vessels. CONCLUSION:Although conventional T1-weighted images were preferred overall, most Silent T1-weighted images were rated as equivalent to or better than conventional images and represent a potential alternative for imaging of noise-averse patients. Silent MRA scored significantly worse and could not be recommended at this time, suggesting that it requires additional refinement before routine clinical use. |
en |
dc.format.medium |
Print-Electronic |
en |
dc.language |
eng |
en |
dc.relation.ispartofseries |
AJR. American journal of roentgenology |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
Humans |
en |
dc.subject |
Brain Neoplasms |
en |
dc.subject |
Meglumine |
en |
dc.subject |
Organometallic Compounds |
en |
dc.subject |
Contrast Media |
en |
dc.subject |
Diagnosis, Differential |
en |
dc.subject |
Magnetic Resonance Imaging |
en |
dc.subject |
Magnetic Resonance Angiography |
en |
dc.subject |
Image Enhancement |
en |
dc.subject |
Adolescent |
en |
dc.subject |
Adult |
en |
dc.subject |
Aged |
en |
dc.subject |
Aged, 80 and over |
en |
dc.subject |
Middle Aged |
en |
dc.subject |
Female |
en |
dc.subject |
Male |
en |
dc.title |
Clinical Evaluation of Silent T1-Weighted MRI and Silent MR Angiography of the Brain. |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.2214/ajr.17.18247 |
en |
pubs.issue |
2 |
en |
pubs.begin-page |
404 |
en |
pubs.volume |
210 |
en |
dc.rights.holder |
Copyright: The author |
en |
dc.identifier.pmid |
29112472 |
en |
pubs.end-page |
411 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Comparative Study |
en |
pubs.subtype |
Journal Article |
en |
pubs.elements-id |
713189 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Medical Sciences |
en |
pubs.org-id |
Anatomy and Medical Imaging |
en |
dc.identifier.eissn |
1546-3141 |
en |
pubs.record-created-at-source-date |
2017-11-08 |
en |
pubs.dimensions-id |
29112472 |
en |