Cost Analysis of Treating Neonatal Hypoglycemia with Dextrose Gel

Show simple item record Glasgow, Matthew en Harding, Jane en Edlin, Richard en 2018-12-02T22:34:21Z en 2018-07 en
dc.identifier.citation The Journal of Pediatrics 198:151-155.e1 Jul 2018 en
dc.identifier.issn 0022-3476 en
dc.identifier.uri en
dc.description.abstract OBJECTIVE:To evaluate the costs of using dextrose gel as a primary treatment for neonatal hypoglycemia in the first 48 hours after birth compared with standard care. STUDY DESIGN:We used a decision tree to model overall costs, including those specific to hypoglycemia monitoring and treatment and those related to the infant's length of stay in the postnatal ward or neonatal intensive care unit, comparing the use of dextrose gel for treatment of neonatal hypoglycemia with placebo, using data from the Sugar Babies randomized trial. Sensitivity analyses assessed the impact of dextrose gel cost, neonatal intensive care cost, cesarean delivery rate, and costs of glucose monitoring. RESULTS:In the primary analysis, treating neonatal hypoglycemia using dextrose gel had an overall cost of NZ$6863.81 and standard care (placebo) cost NZ$8178.25; a saving of NZ$1314.44 per infant treated. Sensitivity analyses showed that dextrose gel remained cost saving with wide variations in dextrose gel costs, neonatal intensive care unit costs, cesarean delivery rates, and costs of monitoring. CONCLUSIONS:Use of buccal dextrose gel reduces hospital costs for management of neonatal hypoglycemia. Because it is also noninvasive, well tolerated, safe, and associated with improved breastfeeding, buccal dextrose gel should be routinely used for initial treatment of neonatal hypoglycemia. TRIAL REGISTRATION:Australian New Zealand Clinical Trials Registry: ACTRN12608000623392. en
dc.format.medium Print-Electronic en
dc.language eng en
dc.publisher Elsevier en
dc.relation.ispartofseries The Journal of Pediatrics en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri en
dc.rights.uri en
dc.subject Children with Hypoglycemia and Their Later Development (CHYLD) Study Team en
dc.subject Humans en
dc.subject Hypoglycemia en
dc.subject Glucose en
dc.subject Gels en
dc.subject Sweetening Agents en
dc.subject Intensive Care, Neonatal en
dc.subject Length of Stay en
dc.subject Decision Trees en
dc.subject Infant, Newborn en
dc.subject Costs and Cost Analysis en
dc.subject Health Resources en
dc.subject New Zealand en
dc.title Cost Analysis of Treating Neonatal Hypoglycemia with Dextrose Gel en
dc.type Journal Article en
dc.identifier.doi 10.1016/j.jpeds.2018.02.036 en
pubs.begin-page 151 en
pubs.volume 198 en
dc.rights.holder Copyright: Elsevier en
dc.identifier.pmid 29625731 en
pubs.end-page 155.e1 en
pubs.publication-status Published en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 735715 en Liggins Institute en LiFePATH en Medical and Health Sciences en Population Health en Gen.Practice& Primary Hlthcare en Health Systems en School of Medicine en Paediatrics Child & Youth Hlth en Psychological Medicine Dept en
dc.identifier.eissn 1097-6833 en
pubs.record-created-at-source-date 2019-07-08 en
pubs.dimensions-id 29625731 en

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