dc.contributor.author |
Jayasinghe, Thilini N |
en |
dc.contributor.author |
Chiavaroli, Valentina |
en |
dc.contributor.author |
Holland, David J |
en |
dc.contributor.author |
Cutfield, Wayne |
en |
dc.contributor.author |
O'Sullivan, Justin |
en |
dc.date.accessioned |
2019-03-18T02:22:03Z |
en |
dc.date.issued |
2016-01 |
en |
dc.identifier.citation |
Frontiers in Cellular and Infection Microbiology 6: 19 Feb 2016 |
en |
dc.identifier.issn |
2235-2988 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/46065 |
en |
dc.description.abstract |
Key Points: The microbiome has been implicated in the development of obesity. Conventional therapeutic methods have limited effectiveness for the treatment of obesity and prevention of related complications. Gut microbiome transplantation may represent an alternative and effective therapy for the treatment of obesity. Obesity has reached epidemic proportions. Despite a better understanding of the underlying pathophysiology and growing treatment options, a significant proportion of obese patients do not respond to treatment. Recently, microbes residing in the human gastrointestinal tract have been found to act as an "endocrine" organ, whose composition and functionality may contribute to the development of obesity. Therefore, fecal/gut microbiome transplantation (GMT), which involves the transfer of feces from a healthy donor to a recipient, is increasingly drawing attention as a potential treatment for obesity. Currently the evidence for GMT effectiveness in the treatment of obesity is preliminary. Here, we summarize benefits, procedures, and issues associated with GMT, with a special focus on obesity. |
en |
dc.format.medium |
Electronic-eCollection |
en |
dc.language |
eng |
en |
dc.relation.ispartofseries |
Frontiers in Cellular and Infection Microbiology |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
en |
dc.subject |
Gastrointestinal Tract |
en |
dc.subject |
Humans |
en |
dc.subject |
Metabolic Diseases |
en |
dc.subject |
Obesity |
en |
dc.subject |
Probiotics |
en |
dc.subject |
Gastrointestinal Microbiome |
en |
dc.subject |
Fecal Microbiota Transplantation |
en |
dc.title |
The New Era of Treatment for Obesity and Metabolic Disorders: Evidence and Expectations for Gut Microbiome Transplantation. |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.3389/fcimb.2016.00015 |
en |
pubs.begin-page |
15 |
en |
pubs.volume |
6 |
en |
dc.rights.holder |
Copyright: The authors |
en |
dc.identifier.pmid |
26925392 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
Research Support, Non-U.S. Gov't |
en |
pubs.subtype |
review-article |
en |
pubs.subtype |
Review |
en |
pubs.subtype |
Journal Article |
en |
pubs.elements-id |
524154 |
en |
pubs.org-id |
Liggins Institute |
en |
dc.identifier.eissn |
2235-2988 |
en |
pubs.record-created-at-source-date |
2016-03-01 |
en |
pubs.dimensions-id |
26925392 |
en |