dc.contributor.author |
Murphy, Rinki |
en |
dc.contributor.author |
Gamble, Gregory |
en |
dc.contributor.author |
House, Meaghan |
en |
dc.contributor.author |
Pool, Bregtina |
en |
dc.contributor.author |
Horne, Anne |
en |
dc.contributor.author |
Merriman, Tony R |
en |
dc.contributor.author |
Dalbeth, Nicola |
en |
dc.date.accessioned |
2019-06-19T01:51:47Z |
en |
dc.date.issued |
2019-02 |
en |
dc.identifier.issn |
1444-0903 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/47185 |
en |
dc.description.abstract |
BACKGROUND:Fructose consumption has been linked with insulin resistance, obesity and diabetes, which are more prevalent in those of Māori or Pacific ethnicity compared to New Zealand European. AIM:To determine whether the acute effects of fructose consumption on serum glucose, insulin, lipids and C-reactive protein differs according to body mass index (BMI) and/or ethnicity. METHODS:Participants of Māori (n = 25), Pacific (n = 26) or New Zealand European (n = 25) ethnicity consumed a 64 g fructose/16 g glucose solution. Changes in lipids, glucose, insulin and C-reactive protein were analysed using mixed models for repeated measures. RESULTS:After adjustment for age and gender, those with higher BMI had a higher glucose (P = 0.0064) and insulin (P = 0.0007) response than those with lower BMI. Those of Māori or Pacific ethnicity had similar glucose levels (P = 0.077) to those of New Zealand European ethnicity but higher insulin responses (P = 0.0005), which remained after additional adjustment for BMI (P = 0.001). Reported sugar-sweetened beverages (SSB) intake was higher among Māori and Pacific than New Zealand European (median 1.0 vs 0.0 SSB/day P = 0.002). CONCLUSION:Even after adjustment for BMI, those of Māori and Pacific ethnicity have a significantly higher insulin response to fructose than New Zealand Europeans. Higher habitual SSB intake may be a contributing factor. |
en |
dc.format.medium |
Print |
en |
dc.language |
eng |
en |
dc.relation.ispartofseries |
Internal medicine journal |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.title |
Greater insulin response to acute fructose ingestion among Māori and Pacific people compared to European people living in Aotearoa New Zealand. |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1111/imj.14135 |
en |
pubs.issue |
2 |
en |
pubs.begin-page |
196 |
en |
pubs.volume |
49 |
en |
dc.rights.holder |
Copyright: The author |
en |
pubs.end-page |
202 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Journal Article |
en |
pubs.elements-id |
763144 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Faculty Administration FMHS |
en |
pubs.org-id |
FMHS Research Support |
en |
pubs.org-id |
School of Medicine |
en |
pubs.org-id |
Medicine Department |
en |
pubs.org-id |
Science |
en |
pubs.org-id |
Science Research |
en |
pubs.org-id |
Maurice Wilkins Centre (2010-2014) |
en |
dc.identifier.eissn |
1445-5994 |
en |
pubs.record-created-at-source-date |
2018-10-10 |
en |
pubs.dimensions-id |
30298971 |
en |