CHAPTER 11: Duocarmycin-PBD Dimers as Antibody-Drug Conjugate (ADC) Payloads

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dc.contributor.author Pillow, TH en
dc.contributor.author Tercel, Moana en
dc.date.accessioned 2019-09-19T03:09:18Z en
dc.date.issued 2019-01-01 en
dc.identifier.isbn 9781788014502 en
dc.identifier.uri http://hdl.handle.net/2292/47793 en
dc.description.abstract © The Royal Society of Chemistry 2019. This chapter describes heterodimeric compounds formed by linking together two different alkylating subunits derived from the duocarmycin and pyrrolobenzodiazepine (PBD) classes of DNA minor groove-alkylating agents. Only a small number of such payloads have been described, their structures are shown in Figure 11.1. en
dc.relation.ispartof RSC Drug Discovery Series en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.title CHAPTER 11: Duocarmycin-PBD Dimers as Antibody-Drug Conjugate (ADC) Payloads en
dc.type Book Item en
dc.identifier.doi 10.1039/9781788012898-00241 en
pubs.begin-page 241 en
pubs.volume 2019-January en
dc.rights.holder Copyright: The author en
pubs.end-page 258 en
pubs.publication-status Published en
dc.rights.accessrights http://purl.org/eprint/accessRights/RestrictedAccess en
pubs.elements-id 779683 en
pubs.org-id Medical and Health Sciences en
pubs.org-id Medical Sciences en
pubs.org-id Auckland Cancer Research en
pubs.org-id Science en
pubs.org-id Science Research en
pubs.org-id Maurice Wilkins Centre (2010-2014) en


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