Design of a Portable Pulsed Power System for Needle-Free Jet Injection

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dc.contributor.author Do, NNL en
dc.contributor.author Taberner, Andrew en
dc.contributor.author Ruddy, Bryan en
dc.coverage.spatial Portland, OR, USA en
dc.date.accessioned 2019-09-29T21:57:44Z en
dc.date.issued 2018-12-06 en
dc.identifier.citation Proceedings 2018 IEEE Energy Conversion Congress and Exposition (ECCE). IEEE. 6633-6640. 06 Dec 2018 en
dc.identifier.isbn 978-1-4799-7312-5 en
dc.identifier.uri http://hdl.handle.net/2292/47985 en
dc.description.abstract Needle-free jet injection (NFJI) is a drug delivery technique that requires the application of a brief (10 ms to 100 ms) pulse of high force to pressurize a liquid drug and force it through the skin. To provide control over this force using an electric motor, high drive power is needed from a compact system. This work outlines the design process of an untethered power and motor drive system that is estimated to weigh approximately 2.5 kg, capable of supplying 1.6 kW at 210 V peak-peak. The device is used to drive a linear synchronous motor to deliver up to 31 large volume (1 mL) needle-free jet injections (NFJI) within a single recharge. The system architecture, gathering of detailed functional requirements, selection of energy storage, and the studies of power electronics and motor drive via system simulation are discussed. Inspired by electric vehicles battery boosted motor drives and cascaded interleaved boost converters for high step-up conversion ratio, the proposed design employs a battery-powered boost converter which then energize a 3-level inverter with the peak to peak voltage of 210 V. The design utilizes the latest gallium nitride (GaN) transistors as well as the latest lithium-ion capacitors (LIC) for energy storage. The power electronic topology introduced in this work is also adaptable for other high energy pulsed applications such as plasma generation, or MRI gradient coils. en
dc.publisher IEEE en
dc.relation.ispartof IEEE Energy Conversion Congress and Exposition en
dc.relation.ispartofseries Proceedings 2018 IEEE Energy Conversion Congress and Exposition (ECCE) en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.rights.uri https://www.ieee.org/publications/rights/author-posting-policy.html en
dc.title Design of a Portable Pulsed Power System for Needle-Free Jet Injection en
dc.type Conference Item en
dc.identifier.doi 10.1109/ECCE.2018.8557608 en
pubs.begin-page 6633 en
dc.rights.holder Copyright: IEEE en
pubs.end-page 6640 en
pubs.finish-date 2018-09-27 en
pubs.start-date 2018-09-23 en
dc.rights.accessrights http://purl.org/eprint/accessRights/OpenAccess en
pubs.subtype Proceedings en
pubs.elements-id 758436 en
pubs.org-id Bioengineering Institute en
pubs.org-id ABI Associates en
pubs.org-id Engineering en
pubs.org-id Engineering Science en
dc.identifier.eissn 2329-3748 en
pubs.record-created-at-source-date 2018-12-18 en
pubs.online-publication-date 2018-12-06 en


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