Socio-Economic Disparity is Not Linked to Outcome Following Heart Transplantation in New Zealand

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Show simple item record Bergin, Colleen en Beliaev, A en Ruygrok, P en 2019-10-01T11:01:29Z en 2019-09-02 en
dc.identifier.issn 1443-9506 en
dc.identifier.uri en
dc.description.abstract Background Socio-economic deprivation (SED) is emerging as a risk factor for acute graft rejection (AR) and reduced survival of heart transplant (HT) recipients. The study aim was to evaluate any association between SED status of HT recipients and the development of early AR and long-term survival in New Zealand. Methods This was a retrospective cohort study. Over a 30-year period, 329 HT recipients were identified from the Australian and New Zealand Heart Transplant Registry. All patients were divided into two groups according to the 2013 New Zealand Deprivation Index (NZDep2013) Score. Heart transplant recipients with NZDep2013 scores of 1,030 and above that corresponded to the eighth, ninth and tenth NZDep2013 deciles were allocated to the higher SED group and those with NZDep2013 scores below 1,030 to the lower SED group. Results The incidence of early AR in the higher SED group was 1.158/person-years and in the lower SED group 1.156/person-years. The crude incidence rate ratio was 1.0 (95% CI: 0.71–1.44; p = 0.9997). The prevalence of early AR in the higher SED group was 1.13/person-years and 1.15/person-years in the lower SED group. The crude prevalence rate ratio was 0.98/person-year (95% CI: 0.68–1.41/person-years; p = 0.468). In the higher SED group, mortality was 5.6/100 person-years (95% CI: 4.3–7.4/100 person-years) and 5.2/100 person-years (95% CI: 4.3–6.3/100 person-years) in the lower SED group. The adjusted mortality rate ratio estimate was 1.2 (95% CI: 0.8–1.7; p = 0.426). The higher and lower SED groups had similar survival (p = 0.196). Conclusion Socio-economic disparity in New Zealand HT recipients has no negative impact on the development of AR or survival. Keywords Socio-economic deprivation Heart transplant Survival Acute graft rejection en
dc.publisher Elsevier en
dc.relation.ispartofseries Heart, Lung and Circulation en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri en
dc.title Socio-Economic Disparity is Not Linked to Outcome Following Heart Transplantation in New Zealand en
dc.type Journal Article en
dc.identifier.doi 10.1016/j.hlc.2019.07.018 en
dc.rights.holder Copyright: The author en
dc.rights.accessrights en
pubs.subtype Article en
pubs.elements-id 780180 en Medical and Health Sciences en Medical Sciences en Anatomy and Medical Imaging en
pubs.record-created-at-source-date 2019-09-09 en
pubs.dimensions-id 31522931 en

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