Randomised trial of the clinical utility of an eyelid massage device for the management of meibomian gland dysfunction.

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dc.contributor.author Wang, Michael en
dc.contributor.author Feng, Jasmine en
dc.contributor.author Wong, Joyce en
dc.contributor.author Turnbull, Philip en
dc.contributor.author Craig, Jennifer en
dc.date.accessioned 2019-10-01T20:51:09Z en
dc.date.issued 2019-12 en
dc.identifier.issn 1367-0484 en
dc.identifier.uri http://hdl.handle.net/2292/48278 en
dc.description.abstract PURPOSE:To compare the single application and two week treatment effects of device-applied (Eyepeace) and manually-applied eyelid massage techniques, as an adjunct to warm compress therapy, on ocular surface and tear film parameters. METHODS:Twenty participants (11 females, 9 males; mean age, 27 ± 11 years) with dry eye symptoms were recruited in a two week, investigator-masked, randomised, contralateral-eye trial. Following 10 min of warm compress therapy application (MGDRx EyeBag®) on both eyes, eyelid massage therapy was applied to one eye (randomised) by device, and to the fellow eye by manual eyelid massage, once daily for 14 days. Ocular surface and tear film measurements were conducted at baseline, and 15 min post-application by a clinician, then again after 14 days of self-administered daily treatment at home. RESULTS:Baseline clinical measurements did not differ between the treatment groups (all p > 0.05). Following two weeks of treatment, tear film lipid layer grade improved significantly with device massage (p = 0.008), and was marginally greater than manual massage by less than 1 grade (p = 0.03). Although immediate post-treatment improvements in tear film stability were observed in both groups (both p < 0.05), no significant long-term cumulative effects or inter-treatment differences in stability measures were detected (all p > 0.05). Visual acuity, tear meniscus height, conjunctival hyperaemia, ocular surface staining, and meibomian gland dropout did not change during the treatment period (all p > 0.05). CONCLUSIONS:Two weeks of treatment with the eyelid massage device, as an adjunct to warm compress therapy, effected marginally greater improvements in tear film lipid layer thickness than the conventional manual technique, which were statistically but not clinically significant. Future parallel group trials with longer treatment periods and a greater range of disease severity are required. en
dc.format.medium Print-Electronic en
dc.language eng en
dc.relation.ispartofseries Contact lens & anterior eye : the journal of the British Contact Lens Association en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.title Randomised trial of the clinical utility of an eyelid massage device for the management of meibomian gland dysfunction. en
dc.type Journal Article en
dc.identifier.doi 10.1016/j.clae.2019.07.008 en
pubs.issue 6 en
pubs.begin-page 620 en
pubs.volume 42 en
dc.rights.holder Copyright: The author en
pubs.end-page 624 en
pubs.publication-status Published en
dc.rights.accessrights http://purl.org/eprint/accessRights/RestrictedAccess en
pubs.subtype Journal Article en
pubs.elements-id 778866 en
pubs.org-id Medical and Health Sciences en
pubs.org-id Optometry and Vision Science en
pubs.org-id School of Medicine en
pubs.org-id Ophthalmology Department en
dc.identifier.eissn 1476-5411 en
pubs.record-created-at-source-date 2019-07-31 en
pubs.dimensions-id 31358441 en


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