dc.contributor.author |
Perez-Ruiz, Fernando |
en |
dc.contributor.author |
Dalbeth, Nicola |
en |
dc.date.accessioned |
2019-10-21T02:38:27Z |
en |
dc.date.issued |
2019-11 |
en |
dc.identifier.issn |
0889-857X |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/48587 |
en |
dc.description.abstract |
The treat to target strategy looks attractive for management of gout because it removes the causal mechanism inducing formation, growth, and aggregation of urate crystals. Further reduction of serum urate (sUA) levels below the threshold may dissolve crystals more rapidly. It is generally agreed that sUA less than 6 mg/dL is acceptable as a therapeutic and long-term preventive target, with <5 mg/dL for the most severe cases. The challenges that this approach in gout is facing include whether proposed targets are the best for desired outcomes, whether they fit patient-related outcomes, and whether they adequately balance effectiveness and safety. |
en |
dc.format.medium |
Print |
en |
dc.language |
eng |
en |
dc.relation.ispartofseries |
Rheumatic diseases clinics of North America |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
Humans |
en |
dc.subject |
Gout |
en |
dc.subject |
Uric Acid |
en |
dc.subject |
Gout Suppressants |
en |
dc.subject |
Risk Reduction Behavior |
en |
dc.subject |
Patient Care Management |
en |
dc.title |
Gout. |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1016/j.rdc.2019.08.001 |
en |
pubs.issue |
4 |
en |
pubs.begin-page |
583 |
en |
pubs.volume |
45 |
en |
dc.rights.holder |
Copyright: The author |
en |
pubs.end-page |
591 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Review |
en |
pubs.subtype |
Journal Article |
en |
pubs.elements-id |
783829 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
School of Medicine |
en |
pubs.org-id |
Medicine Department |
en |
dc.identifier.eissn |
1558-3163 |
en |
pubs.record-created-at-source-date |
2019-10-01 |
en |
pubs.dimensions-id |
31564298 |
en |