dc.contributor.author |
Laing, Bobbi |
en |
dc.contributor.author |
Lim, Anecita |
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dc.contributor.author |
Ferguson, Lynnette |
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dc.date.accessioned |
2019-10-21T22:37:16Z |
en |
dc.date.issued |
2019-07-05 |
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dc.identifier.citation |
Nutrients 11(7) 05 Jul 2019 |
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dc.identifier.issn |
2072-6643 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/48594 |
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dc.description.abstract |
This review discusses the personalised dietary approach with respect to inflammatory bowel disease (IBD). It identifies gene-nutrient interactions associated with the nutritional deficiencies that people with IBD commonly experience, and the role of the Western diet in influencing these. It also discusses food intolerances and how particular genotypes can affect these. It is well established that with respect to food there is no "one size fits all" diet for those with IBD. Gene-nutrient interactions may help explain this variability in response to food that is associated with IBD. Nutrigenomic research, which examines the effects of food and its constituents on gene expression, shows that-like a number of pharmaceutical products-food can have beneficial effects or have adverse (side) effects depending on a person's genotype. Pharmacogenetic research is identifying gene variants with adverse reactions to drugs, and this is modifying clinical practice and allowing individualised treatment. Nutrigenomic research could enable individualised treatment in persons with IBD and enable more accurate tailoring of food intake, to avoid exacerbating malnutrition and to counter some of the adverse effects of the Western diet. It may also help to establish the dietary pattern that is most protective against IBD. |
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dc.format.medium |
Electronic |
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dc.language |
eng |
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dc.relation.ispartofseries |
Nutrients |
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dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
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dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
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dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
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dc.subject |
Animals |
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dc.subject |
Humans |
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dc.subject |
Inflammatory Bowel Diseases |
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dc.subject |
Deficiency Diseases |
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dc.subject |
Food Hypersensitivity |
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dc.subject |
Treatment Outcome |
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dc.subject |
Risk Factors |
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dc.subject |
Feeding Behavior |
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dc.subject |
Nutritional Status |
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dc.subject |
Nutritive Value |
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dc.subject |
Adolescent |
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dc.subject |
Adult |
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dc.subject |
Middle Aged |
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dc.subject |
Child |
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dc.subject |
Female |
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dc.subject |
Male |
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dc.subject |
Nutrigenomics |
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dc.subject |
Adolescent Nutritional Physiological Phenomena |
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dc.subject |
Young Adult |
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dc.subject |
Child Nutritional Physiological Phenomena |
en |
dc.subject |
Gene-Environment Interaction |
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dc.subject |
Diet, Western |
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dc.subject |
Precision Medicine |
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dc.title |
A Personalised Dietary Approach-A Way Forward to Manage Nutrient Deficiency, Effects of the Western Diet, and Food Intolerances in Inflammatory Bowel Disease. |
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dc.type |
Journal Article |
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dc.identifier.doi |
10.3390/nu11071532 |
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pubs.issue |
7 |
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pubs.volume |
11 |
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dc.rights.holder |
Copyright: The authors |
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pubs.publication-status |
Published |
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dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
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pubs.subtype |
review-article |
en |
pubs.subtype |
Review |
en |
pubs.subtype |
Journal Article |
en |
pubs.elements-id |
777190 |
en |
pubs.org-id |
Medical and Health Sciences |
en |
pubs.org-id |
Nursing |
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dc.identifier.eissn |
2072-6643 |
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pubs.record-created-at-source-date |
2019-07-10 |
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pubs.dimensions-id |
31284450 |
en |