An update on the role of gut microbiota in chronic inflammatory diseases, and potential therapeutic targets.

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dc.contributor.author Laing, Bobbi en
dc.contributor.author Barnett, Matthew en
dc.contributor.author Marlow, Gareth en
dc.contributor.author Nasef, Noha Ahmed en
dc.contributor.author Ferguson, Lynnette en
dc.date.accessioned 2019-11-03T21:46:11Z en
dc.date.issued 2018-10 en
dc.identifier.issn 1747-4124 en
dc.identifier.uri http://hdl.handle.net/2292/48805 en
dc.description.abstract INTRODUCTION:The human microbiome plays a critical role in human health, having metabolic, protective, and trophic functions, depending upon its' exact composition. This composition is affected by a number of factors, including the genetic background of the individual, early life factors (including method of birth, length of breastfeeding) and nature of the diet and other environmental exposures (including cigarette smoking) and general life habits. It plays a key role in the control of inflammation, and in turn, its' composition is significantly influenced by inflammation. Areas covered: We consider metabolic, protective, and trophic functions of the microbiome and influences through the lifespan from post-partum effects, to diet later in life in healthy older adults, the effects of aging on both its' composition, and influence on health and potential therapeutic targets that may have anti-inflammatory effects. Expert commentary: The future will see the growth of more effective therapies targeting the microbiome particularly with respect to the use of specific nutrients and diets personalized to the individual. en
dc.format.medium Print-Electronic en
dc.language eng en
dc.relation.ispartofseries Expert review of gastroenterology & hepatology en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.title An update on the role of gut microbiota in chronic inflammatory diseases, and potential therapeutic targets. en
dc.type Journal Article en
dc.identifier.doi 10.1080/17474124.2018.1505497 en
pubs.issue 10 en
pubs.begin-page 969 en
pubs.volume 12 en
dc.rights.holder Copyright: The author en
pubs.end-page 983 en
pubs.publication-status Published en
dc.rights.accessrights http://purl.org/eprint/accessRights/RestrictedAccess en
pubs.subtype Journal Article en
pubs.elements-id 755288 en
pubs.org-id Medical and Health Sciences en
pubs.org-id Nursing en
dc.identifier.eissn 1747-4132 en
pubs.record-created-at-source-date 2018-07-28 en
pubs.dimensions-id 30052094 en


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