Newborn pulse oximetry screening in the context of a high antenatal detection rate of critical congenital heart disease.

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dc.contributor.author Cloete, Hester en
dc.contributor.author Bloomfield, Francis en
dc.contributor.author Cassells, Sharnie A en
dc.contributor.author de Laat, Monique WM en
dc.contributor.author Sadler, Lynn en
dc.contributor.author Gentles, Thomas L en
dc.date.accessioned 2020-01-10T01:11:46Z en
dc.date.issued 2020-01 en
dc.identifier.citation Acta paediatrica (Oslo, Norway : 1992) 23 Jul 2019 en
dc.identifier.issn 0803-5253 en
dc.identifier.uri http://hdl.handle.net/2292/49476 en
dc.description.abstract AIM:Assess the potential additional benefit from pulse oximetry screening in the early detection of critical congenital heart disease in a country with a well-developed antenatal ultrasound screening programme. METHODS:Live-born infants, pregnancy terminations and stillbirths from 20 weeks' gestational age, between 2013 and 2015, with critical cardiac defects defined as primary or secondary targets of pulse oximetry screening were identified. Critical defects were those resulting in the death of a fetus or an infant in the first 28 days after birth, or a defect requiring intervention in the first 28 days. RESULTS:Two hundred and sixty-eight infants and Fetuses were identified. Antenatal detection rates improved from 69% to 77% over the study period. An associated co-morbidity improved antenatal detection rates. Twenty-seven live-born infants were diagnosed after discharge: 15 aortic arch obstruction (AAO); 10 d-loop transposition of the great arteries (d-TGA), and two total anomalous pulmonary venous drainage (TAPVD). Of these, five with AAO, nine with d-TGA and likely both with TAPVD could potentially have been detected with oximetry screening. CONCLUSION:The antenatal detection of critical cardiac anomalies continues to improve in New Zealand. Despite high antenatal detection rates for most lesions, universal postnatal oximetry screening has the potential to improve early detection. en
dc.format.medium Print-Electronic en
dc.language eng en
dc.relation.ispartofseries Acta paediatrica (Oslo, Norway : 1992) en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.rights.uri https://creativecommons.org/licenses/by-nc/4.0/ en
dc.title Newborn pulse oximetry screening in the context of a high antenatal detection rate of critical congenital heart disease. en
dc.type Journal Article en
dc.identifier.doi 10.1111/apa.14946 en
pubs.issue 1 en
pubs.begin-page 93 en
pubs.volume 109 en
dc.rights.holder Copyright: The authors en
pubs.end-page 99 en
pubs.publication-status Published en
dc.rights.accessrights http://purl.org/eprint/accessRights/OpenAccess en
pubs.subtype Research Support, Non-U.S. Gov't en
pubs.subtype research-article en
pubs.subtype Journal Article en
pubs.elements-id 780011 en
pubs.org-id Liggins Institute en
pubs.org-id LiFePATH en
pubs.org-id Medical and Health Sciences en
pubs.org-id School of Medicine en
pubs.org-id Obstetrics and Gynaecology en
dc.identifier.eissn 1651-2227 en
pubs.record-created-at-source-date 2019-07-24 en
pubs.dimensions-id 31332832 en


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