An investigation into the effect of ribosomal protein S15 phosphorylation on its intermolecular interactions by using phosphomimetic mutant.

Correddu, Danilo; Sharma, Nabangshu; Kaur, Simranjeet; Varnava, Kyriakos; Mbenza, Naasson Mbambi; Sarojini, Vijayalekshmi; Leung, Ka Ho Ivanhoe

dc.contributor.author	Correddu, Danilo	en
dc.contributor.author	Sharma, Nabangshu	en
dc.contributor.author	Kaur, Simranjeet	en
dc.contributor.author	Varnava, Kyriakos	en
dc.contributor.author	Mbenza, Naasson Mbambi	en
dc.contributor.author	Sarojini, Vijayalekshmi	en
dc.contributor.author	Leung, Ka Ho Ivanhoe	en
dc.date.accessioned	2020-07-09T21:31:44Z	en
dc.date.issued	2020-07	en
dc.identifier.citation	Chemical communications (Cambridge, England) 25 Jun 2020	en
dc.identifier.citation	Chemical communications 56(57):7857-7860 Jul 2020
dc.identifier.issn	1359-7345	en
dc.identifier.uri	http://hdl.handle.net/2292/52389	en
dc.description.abstract	An investigation using recombinant ribosomal proteins and synthetic peptide models was conducted to uncover the effect of the introduction of a negative charge at the C-terminal tail of ribosomal protein S15. Our results help provide a chemical rationale towards understanding how G2019S LRRK2, a common clinical mutation, causes Parkinson's disease.	en
dc.format.medium	Print-Electronic	en
dc.language	eng	en
dc.relation.ispartofseries	Chemical communications (Cambridge, England)	en
dc.rights	Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.	en
dc.rights.uri	https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm	en
dc.rights.uri	https://www.rsc.org/journals-books-databases/open-access/green-open-access/	en
dc.title	An investigation into the effect of ribosomal protein S15 phosphorylation on its intermolecular interactions by using phosphomimetic mutant.	en
dc.type	Journal Article	en
dc.identifier.doi	10.1039/d0cc01618g	en
pubs.issue	57	en
pubs.begin-page	7857	en
pubs.volume	56	en
dc.rights.holder	Copyright: The Royal Society of Chemistry	en
pubs.end-page	7860	en
pubs.publication-status	Published	en
dc.rights.accessrights	http://purl.org/eprint/accessRights/OpenAccess	en
pubs.subtype	Journal Article	en
pubs.elements-id	804828	en
pubs.org-id	Medical and Health Sciences	en
pubs.org-id	Medical Sciences	en
pubs.org-id	Physiology Division	en
pubs.org-id	Science	en
pubs.org-id	Chemistry	en
dc.identifier.eissn	1364-548X	en
pubs.record-created-at-source-date	2020-06-26	en
pubs.dimensions-id	32583822	en