dc.contributor.author |
Grimsey Natasha L |
en |
dc.contributor.author |
Savinainen Juha R |
en |
dc.contributor.author |
Attili Bala |
en |
dc.contributor.author |
Ahamed Muneer |
en |
dc.date.accessioned |
2020-10-16T00:49:47Z |
|
dc.date.available |
2020-10-16T00:49:47Z |
|
dc.date.issued |
2019-10-14 |
en |
dc.identifier.citation |
Drug discovery today 14 Oct 2019 |
|
dc.identifier.issn |
1359-6446 |
en |
dc.identifier.uri |
http://hdl.handle.net/2292/53320 |
|
dc.description.abstract |
Monoacylglycerol lipase (MAGL) is a major endocannabinoid hydrolyzing enzyme and can be regulated to control endogenous lipid levels in the brain. This review highlights the pharmacological roles and in vivo PET imaging of MAGL in brain. |
en |
dc.format.medium |
Print-Electronic |
en |
dc.language |
eng |
en |
dc.publisher |
ELSEVIER SCI LTD |
en |
dc.relation.ispartofseries |
Drug discovery today |
en |
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
en |
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
en |
dc.subject |
1109 Neurosciences |
en |
dc.subject |
Biomedical |
en |
dc.subject |
Basic Science |
en |
dc.subject |
Substance Abuse |
en |
dc.subject |
Diagnostic Radiology |
en |
dc.subject |
Neurosciences |
en |
dc.subject |
Drug Abuse (NIDA Only) |
en |
dc.subject |
Neurological |
en |
dc.subject |
Science & Technology |
en |
dc.subject |
Life Sciences & Biomedicine |
en |
dc.subject |
Pharmacology & Pharmacy |
en |
dc.subject |
HIGHLY SELECTIVE INHIBITORS |
en |
dc.subject |
ACID AMIDE HYDROLASE |
en |
dc.subject |
MONOGLYCERIDE LIPASE |
en |
dc.subject |
CANNABINOID RECEPTOR |
en |
dc.subject |
MOUSE MODEL |
en |
dc.subject |
ENDOCANNABINOID SYSTEM |
en |
dc.subject |
PRECLINICAL EVALUATION |
en |
dc.subject |
COVALENT INHIBITORS |
en |
dc.subject |
MASS-SPECTROMETRY |
en |
dc.subject |
CRYSTAL-STRUCTURE |
en |
dc.subject |
1115 Pharmacology And Pharmaceutical Sciences |
en |
dc.title |
Regulating membrane lipid levels at the synapse by small-molecule inhibitors of monoacylglycerol lipase: new developments in therapeutic and PET imaging applications. |
en |
dc.type |
Journal Article |
en |
dc.identifier.doi |
10.1016/j.drudis.2019.10.004 |
en |
pubs.issue |
2 |
en |
pubs.begin-page |
330 |
en |
pubs.volume |
25 |
en |
dc.date.updated |
2020-09-08T04:45:54Z |
en |
dc.rights.holder |
Copyright: 2019 Elsevier |
en |
pubs.author-url |
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000517657800009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=6e41486220adb198d0efde5a3b153e7d |
en |
pubs.end-page |
343 |
en |
pubs.publication-status |
Published |
en |
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Review |
en |
pubs.subtype |
Journal Article |
en |
pubs.elements-id |
785146 |
en |
dc.identifier.eissn |
1878-5832 |
en |