Omega-3 fats in pregnancy: could a targeted approach lead to better metabolic health for children?

Show simple item record Satokar, Vidit V Cutfield, Wayne S Cameron-Smith, David Albert, Benjamin B 2020-12-08T21:00:50Z 2020-12-08T21:00:50Z 2020-9-24
dc.identifier.issn 0029-6643
dc.description.abstract The prevalence of childhood obesity is increasing worldwide, and the children of women who are obese during pregnancy are at greatest risk. This risk may be mediated by exaggeration of the normal insulin resistance of pregnancy. Omega-3 (n-3) fats are insulin sensitizing. Supplementation during pregnancy may reduce metabolic risk and adiposity in the children. Though results from animal studies are encouraging, completed clinical trials have not demonstrated this benefit. However, to our knowledge, previous studies have not targeted women who are overweight or obese while pregnant-the group at greatest risk for insulin resistance and most likely to benefit from n-3. In this narrative review, the importance of performing clinical trials restricted to women who are overweight or obese is discussed, as is the potential importance of n-3 dose, oil source and quality, and the timing of the intervention.
dc.format.medium Print-Electronic
dc.language eng
dc.publisher Oxford University Press (OUP)
dc.relation.ispartofseries Nutrition reviews
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.
dc.subject 1114 Paediatrics and Reproductive Medicine
dc.subject 1103 Clinical Sciences
dc.subject Clinical
dc.subject Clinical Medicine and Science
dc.subject Obesity
dc.subject Nutrition
dc.subject Prevention
dc.subject Clinical Trials and Supportive Activities
dc.subject Complementary and Alternative Medicine
dc.subject Clinical Research
dc.subject Pediatric
dc.subject Cardiovascular
dc.subject Metabolic and Endocrine
dc.subject Cancer
dc.subject Reproductive Health and Childbirth
dc.subject 11 Medical and Health Sciences
dc.subject 17 Psychology and Cognitive Sciences
dc.title Omega-3 fats in pregnancy: could a targeted approach lead to better metabolic health for children?
dc.type Journal Article
dc.identifier.doi 10.1093/nutrit/nuaa071 2020-11-09T23:06:37Z
dc.rights.holder Copyright: The author en
pubs.publication-status Published
dc.rights.accessrights en
pubs.subtype Journal Article
pubs.elements-id 820353
dc.identifier.eissn 1753-4887 2020-9-24

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