dc.contributor.author |
Palmada, Nadun |
|
dc.contributor.author |
Cater, John E |
|
dc.contributor.author |
Cheng, Leo K |
|
dc.contributor.author |
Suresh, Vinod |
|
dc.coverage.spatial |
United States |
|
dc.date.accessioned |
2021-01-13T03:17:08Z |
|
dc.date.available |
2021-01-13T03:17:08Z |
|
dc.date.issued |
2020-7 |
|
dc.identifier.isbn |
9781728119908 |
|
dc.identifier.issn |
2375-7477 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/54202 |
|
dc.description.abstract |
The small intestine is the primary site of enzymatic digestion and nutrient absorption in humans. Intestinal contractions facilitate digesta mixing, transport and contact with the absorptive surfaces. These motility patterns are regulated by an underlying electrical activity, termed slow waves. In this study, we use computational fluid dynamics simulation of flow and mixing of intestinal contents in the human duodenum with anatomically realistic geometry and contraction patterns. Parameters including the amplitude of contraction (10-50% reduction of radius) and the rheology of the digesta (Newtonian vs Non-Newtonian power law fluid) were altered in-order to study their effects on mixing. Interesting flow features such as stagnation points and reversed flow were observed with digesta. Increases in the amplitude of contraction lead to increased propulsion of digesta along the intestine and increased mixing. |
|
dc.format.medium |
Print |
|
dc.publisher |
IEEE |
|
dc.relation.ispartof |
2020 42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) in conjunction with the 43rd Annual Conference of the Canadian Medical and Biological Engineering Society |
|
dc.relation.ispartofseries |
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.subject |
Intestines |
|
dc.subject |
Intestine, Small |
|
dc.subject |
Duodenum |
|
dc.subject |
Gastrointestinal Contents |
|
dc.subject |
Humans |
|
dc.subject |
Rheology |
|
dc.subject |
Duodenum |
|
dc.subject |
Gastrointestinal Contents |
|
dc.subject |
Humans |
|
dc.subject |
Intestine, Small |
|
dc.subject |
Intestines |
|
dc.subject |
Rheology |
|
dc.title |
Modelling Flow and Mixing in the Proximal Small Intestine. |
|
dc.type |
Conference Item |
|
dc.identifier.doi |
10.1109/embc44109.2020.9176688 |
|
pubs.begin-page |
2496 |
|
pubs.volume |
2020 |
|
dc.date.updated |
2020-12-03T23:50:21Z |
|
dc.rights.holder |
Copyright: The author |
en |
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/33018513 |
|
pubs.end-page |
2499 |
|
pubs.finish-date |
2020-7-24 |
|
pubs.publication-status |
Published |
|
pubs.start-date |
2020-7-20 |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.elements-id |
817463 |
|
dc.identifier.eissn |
2694-0604 |
|