dc.contributor.author |
Geoghegan, Jemma L |
|
dc.contributor.author |
Ren, Xiaoyun |
|
dc.contributor.author |
Storey, Matthew |
|
dc.contributor.author |
Hadfield, James |
|
dc.contributor.author |
Jelley, Lauren |
|
dc.contributor.author |
Jefferies, Sarah |
|
dc.contributor.author |
Sherwood, Jill |
|
dc.contributor.author |
Paine, Shevaun |
|
dc.contributor.author |
Huang, Sue |
|
dc.contributor.author |
Douglas, Jordan |
|
dc.contributor.author |
Mendes, Fábio K |
|
dc.contributor.author |
Sporle, Andrew |
|
dc.contributor.author |
Baker, Michael G |
|
dc.contributor.author |
Murdoch, David R |
|
dc.contributor.author |
French, Nigel |
|
dc.contributor.author |
Simpson, Colin R |
|
dc.contributor.author |
Welch, David |
|
dc.contributor.author |
Drummond, Alexei J |
|
dc.contributor.author |
Holmes, Edward C |
|
dc.contributor.author |
Duchêne, Sebastián |
|
dc.contributor.author |
de Ligt, Joep |
|
dc.coverage.spatial |
England |
|
dc.date.accessioned |
2021-02-15T23:30:51Z |
|
dc.date.available |
2021-02-15T23:30:51Z |
|
dc.date.issued |
2020-12-11 |
|
dc.identifier.citation |
Nature communications 11(1):6351 11 Dec 2020 |
|
dc.identifier.issn |
2041-1723 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/54466 |
|
dc.description.abstract |
New Zealand, a geographically remote Pacific island with easily sealable borders, implemented a nationwide 'lockdown' of all non-essential services to curb the spread of COVID-19. Here, we generate 649 SARS-CoV-2 genome sequences from infected patients in New Zealand with samples collected during the 'first wave', representing 56% of all confirmed cases in this time period. Despite its remoteness, the viruses imported into New Zealand represented nearly all of the genomic diversity sequenced from the global virus population. These data helped to quantify the effectiveness of public health interventions. For example, the effective reproductive number, R<sub>e</sub> of New Zealand's largest cluster decreased from 7 to 0.2 within the first week of lockdown. Similarly, only 19% of virus introductions into New Zealand resulted in ongoing transmission of more than one additional case. Overall, these results demonstrate the utility of genomic pathogen surveillance to inform public health and disease mitigation. |
|
dc.format.medium |
Electronic |
|
dc.language |
eng |
|
dc.publisher |
Springer Science and Business Media LLC |
|
dc.relation.ispartofseries |
Nature communications |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
|
dc.title |
Genomic epidemiology reveals transmission patterns and dynamics of SARS-CoV-2 in Aotearoa New Zealand. |
|
dc.type |
Journal Article |
|
dc.identifier.doi |
10.1038/s41591-020-0869-5 |
|
pubs.issue |
1 |
|
pubs.begin-page |
6351 |
|
pubs.volume |
11 |
|
dc.date.updated |
2021-01-04T20:10:51Z |
|
dc.rights.holder |
Copyright: The authors |
en |
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/33311501 |
|
pubs.publication-status |
Published |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
Research Support, Non-U.S. Gov't |
|
pubs.subtype |
research-article |
|
pubs.subtype |
Journal Article |
|
pubs.elements-id |
832794 |
|
dc.identifier.eissn |
2041-1723 |
|
dc.identifier.pii |
10.1038/s41467-020-20235-8 |
|
pubs.number |
6351 |
|
pubs.online-publication-date |
2020-12-11 |
|