dc.contributor.author |
Lu, Louise W |
|
dc.contributor.author |
Silvestre, Marta P |
|
dc.contributor.author |
Sequeira, Ivana R |
|
dc.contributor.author |
Plank, Lindsay D |
|
dc.contributor.author |
Foster, Meika |
|
dc.contributor.author |
Middleditch, Nikki |
|
dc.contributor.author |
Acevedo-Fani, Alejandra |
|
dc.contributor.author |
Hollingsworth, Kieren G |
|
dc.contributor.author |
Poppitt, Sally D |
|
dc.date.accessioned |
2021-06-15T02:58:57Z |
|
dc.date.available |
2021-06-15T02:58:57Z |
|
dc.date.issued |
2021-4-23 |
|
dc.identifier.citation |
Journal of nutritional science 10:e30 Jan 2021 |
|
dc.identifier.issn |
2048-6790 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/55315 |
|
dc.description.abstract |
Nut-based products may aid low-glycaemic dietary strategies that are important for diabetes prevention in populations at increased risk of dysglycaemia, such as Asian Chinese. This randomised cross-over trial assessed the postprandial glycaemic response (0-120 min) of a higher-protein nut-based (HP-NB) snack formulation, in bar format (1009 kJ, Nutrient Profiling Score, NPS, -2), when compared with an iso-energetic higher-carbohydrate (CHO) cereal-based bar (HC-CB, 985 kJ, NPS +3). It also assessed the ability to suppress glucose response to a typical CHO-rich food (white bread, WB), when co-ingested. Ten overweight prediabetic Chinese adults (mean, sd: age 47⋅9, 15⋅7 years; BMI 25⋅5, 1⋅6 kg/m2), with total body fat plus ectopic pancreas and liver fat quantified using dual-energy X-ray absorptiometry and magnetic resonance imaging and spectroscopy, received the five meal treatments in random order: HP-NB, HC-CB, HP-NB + WB (50 g available CHO), HC-CB + WB and WB only. Compared with HC-CB, HP-NB induced a significantly lower 30-120 min glucose response (P < 0⋅05), with an approximately 10-fold lower incremental area under the glucose curve (iAUC0-120; P < 0⋅001). HP-NB also attenuated glucose response by approximately 25 % when co-ingested with WB (P < 0⋅05). Half of the cohort had elevated pancreas and/or liver fat, with 13-21 % greater suppression of iAUC0-120 glucose in the low v. high organ fat subgroups across all five treatments. A nut-based snack product may be a healthier alternative to an energy equivalent cereal-based product with evidence of both a lower postprandial glycaemic response and modulation of CHO-induced hyperglycaemia even in high-risk, overweight, pre-diabetic adults. |
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dc.language |
en |
|
dc.publisher |
Cambridge University Press (CUP) |
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dc.relation.ispartofseries |
Journal of Nutritional Science |
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dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.rights.uri |
https://www.cambridge.org/core/journals/journal-of-nutritional-science/information/open-access |
|
dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
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dc.subject |
Science & Technology |
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dc.subject |
Life Sciences & Biomedicine |
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dc.subject |
Nutrition & Dietetics |
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dc.subject |
Dried fruits |
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dc.subject |
MRI |
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dc.subject |
Nuts |
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dc.subject |
Postprandial glycaemia |
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dc.subject |
Prediabetes |
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dc.subject |
1111 Nutrition and Dietetics |
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dc.title |
A higher-protein nut-based snack product suppresses glycaemia and decreases glycaemic response to co-ingested carbohydrate in an overweight prediabetic Asian Chinese cohort: the Tū Ora postprandial RCT |
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dc.type |
Journal Article |
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dc.identifier.doi |
10.1017/jns.2021.20 |
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pubs.begin-page |
e30 |
|
pubs.volume |
10 |
|
dc.date.updated |
2021-05-13T21:24:31Z |
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dc.rights.holder |
Copyright: The author |
en |
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/34094511 |
|
pubs.publication-status |
Published |
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dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
Article |
|
pubs.subtype |
Journal |
|
pubs.elements-id |
851277 |
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dc.identifier.eissn |
2048-6790 |
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pubs.number |
e30 |
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pubs.online-publication-date |
2021-4-23 |
|