Use of Genomics to Track Coronavirus Disease Outbreaks, New Zealand.

Show simple item record Geoghegan, Jemma L Douglas, Jordan Ren, Xiaoyun Storey, Matthew Hadfield, James Silander, Olin K Freed, Nikki E Jelley, Lauren Jefferies, Sarah Sherwood, Jillian Paine, Shevaun Huang, Sue Sporle, Andrew Baker, Michael G Murdoch, David R Drummond, Alexei J Welch, David Simpson, Colin R French, Nigel Holmes, Edward C de Ligt, Joep
dc.coverage.spatial United States 2021-06-15T03:30:52Z 2021-06-15T03:30:52Z 2021-5
dc.identifier.citation Emerging infectious diseases 27(5):1317-1322 May 2021
dc.identifier.issn 1080-6040
dc.description.abstract Real-time genomic sequencing has played a major role in tracking the global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), contributing greatly to disease mitigation strategies. In August 2020, after having eliminated the virus, New Zealand experienced a second outbreak. During that outbreak, New Zealand used genomic sequencing in a primary role, leading to a second elimination of the virus. We generated genomes from 78% of the laboratory-confirmed samples of SARS-CoV-2 from the second outbreak and compared them with the available global genomic data. Genomic sequencing rapidly identified that virus causing the second outbreak in New Zealand belonged to a single cluster, thus resulting from a single introduction. However, successful identification of the origin of this outbreak was impeded by substantial biases and gaps in global sequencing data. Access to a broader and more heterogenous sample of global genomic data would strengthen efforts to locate the source of any new outbreaks.
dc.format.medium Print
dc.language eng
dc.publisher Centers for Disease Control and Prevention (CDC)
dc.relation.ispartofseries Emerging infectious diseases
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.
dc.subject 2019 novel coronavirus disease
dc.subject COVID-19
dc.subject New Zealand
dc.subject SARS-CoV-2
dc.subject coronavirus disease
dc.subject genomics
dc.subject infectious disease
dc.subject respiratory infections
dc.subject severe acute respiratory syndrome coronavirus 2
dc.subject viruses
dc.subject zoonoses
dc.subject 1103 Clinical Sciences
dc.subject 1108 Medical Microbiology
dc.subject 1117 Public Health and Health Services
dc.title Use of Genomics to Track Coronavirus Disease Outbreaks, New Zealand.
dc.type Journal Article
dc.identifier.doi 10.3201/eid2705.204579
pubs.issue 5
pubs.begin-page 1317
pubs.volume 27 2021-05-18T19:29:27Z
dc.rights.holder Copyright: The author en
pubs.end-page 1322
pubs.publication-status Published
dc.rights.accessrights en
pubs.subtype research-article
pubs.subtype Journal Article
pubs.elements-id 853035
dc.identifier.eissn 1080-6059

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