Identifying potential classification criteria for calcium pyrophosphate deposition disease (CPPD): Item generation and item reduction.

Show simple item record Tedeschi, Sara K Pascart, Tristan Latourte, Augustin Godsave, Cattleya Kundakci, Burak Naden, Raymond P Taylor, William J Dalbeth, Nicola Neogi, Tuhina Perez-Ruiz, Fernando Rosenthal, Ann Becce, Fabio Pascual, Eliseo Andres, Mariano Bardin, Thomas Doherty, Michael Ea, Hang-Korng Filippou, Georgios FitzGerald, John Guitierrez, Marwin Iagnocco, Annamaria Jansen, Tim L Kohler, Minna J Lioté, Frédéric Matza, Mark McCarthy, Geraldine M Ramonda, Roberta Reginato, Anthony M Richette, Pascal Singh, Jasvinder A Sivera, Francisca So, Alexander Stamp, Lisa K Yinh, Janeth Yokose, Chio Terkeltaub, Robert Choi, Hyon Abhishek, Abhishek
dc.coverage.spatial United States 2021-06-16T21:52:57Z 2021-06-16T21:52:57Z 2021-5-10
dc.identifier.citation Arthritis care & research 10 May 2021
dc.identifier.issn 2151-464X
dc.description.abstract <h4>Objective</h4>Classification criteria for calcium pyrophosphate deposition disease (CPPD) will facilitate clinical research on this common crystalline arthritis. We report on the first two phases of a four-phase process for developing CPPD classification criteria.<h4>Methods</h4>CPPD classification criteria development is overseen by a 12-member Steering Committee. Item generation (Phase I) included a scoping literature review of five literature databases and contributions from a 35-member Combined Expert Committee and two Patient Research Partners. Item reduction and refinement (Phase II) involved a Combined Expert Committee meeting, discussions among Clinical, Imaging, and Laboratory Advisory Groups, and an item rating exercise to assess the influence of individual items toward classification. The Steering Committee reviewed the modal rating score for each item (range -3 [strongly pushes away from CPPD] to +3 [strongly pushes toward CPPD]) to determine items to retain for future phases of criteria development.<h4>Results</h4>Item generation yielded 420 items (312 from the literature, 108 from experts/patients). The Advisory Groups eliminated items they agreed were unlikely to distinguish between CPPD and other forms of arthritis, yielding 127 items for the item rating exercise. Fifty-six items, most of which had a modal rating of +/- 2 or 3, were retained for future phases. As numerous imaging items were rated +3, the Steering Committee recommended focusing on imaging of the knee, wrist, and one additional affected joint for calcification suggestive of CPP crystal deposition.<h4>Conclusion</h4>A data- and expert-driven process is underway to develop CPPD classification criteria. Candidate items comprise clinical, imaging, and laboratory features.
dc.format.medium Print-Electronic
dc.language eng
dc.publisher Wiley
dc.relation.ispartofseries Arthritis care & research
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.
dc.rights his is the pre-peer reviewed version of the following article: Arthritis care & research 10 May 2021, which has been published in final form at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
dc.subject CPPD
dc.subject calcium pyrophosphate
dc.subject classification criteria
dc.subject pseudogout
dc.subject 1103 Clinical Sciences
dc.subject 1117 Public Health and Health Services
dc.subject 1701 Psychology
dc.title Identifying potential classification criteria for calcium pyrophosphate deposition disease (CPPD): Item generation and item reduction.
dc.type Journal Article
dc.identifier.doi 10.1002/acr.24619 2021-05-20T04:21:19Z
dc.rights.holder Copyright: The author en
pubs.publication-status Published
dc.rights.accessrights en
pubs.subtype Journal Article
pubs.elements-id 852403
dc.identifier.eissn 2151-4658
pubs.number acr.24619 2021-5-10

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