dc.contributor.author |
Shrestha, Aahana |
|
dc.contributor.author |
Prodhan, Utpal K |
|
dc.contributor.author |
Mitchell, Sarah M |
|
dc.contributor.author |
Sharma, Pankaja |
|
dc.contributor.author |
Barnett, Matthew PG |
|
dc.contributor.author |
Milan, Amber M |
|
dc.contributor.author |
Cameron-Smith, David |
|
dc.coverage.spatial |
Switzerland |
|
dc.date.accessioned |
2021-06-21T21:44:26Z |
|
dc.date.available |
2021-06-21T21:44:26Z |
|
dc.date.issued |
2019-7-17 |
|
dc.identifier.citation |
Nutrients 11(7) 17 Jul 2019 |
|
dc.identifier.issn |
2072-6643 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/55368 |
|
dc.description.abstract |
Hydrogen (H<sub>2</sub>) measurement in exhaled breath is a reliable and non-invasive method to diagnose carbohydrate malabsorption. Currently, breath H<sub>2</sub> measurement is typically limited to clinic-based equipment. A portable breath analyser (AIRE, FoodMarble Digestive Health Limited, Dublin, Ireland) is a personalised device marketed for the detection and self-management of food intolerances, including lactose malabsorption (LM). Currently, the validity of this device for breath H<sub>2</sub> analysis is unknown. Individuals self-reporting dairy intolerance (six males and six females) undertook a lactose challenge and a further seven individuals (all females) underwent a milk challenge. Breath samples were collected prior to and at frequent intervals post-challenge for up to 5 h with analysis using both the AIRE and a calibrated breath hydrogen analyser (BreathTracker, QuinTron Instrument Company Inc., Milwaukee, WI, USA). A significant positive correlation (<i>p</i> < 0.001, r > 0.8) was demonstrated between AIRE and BreathTracker H<sub>2</sub> values, after both lactose and milk challenges, although 26% of the AIRE readings demonstrated the maximum score of 10.0 AU. Based on our data, the cut-off value for LM diagnosis (25 ppm H<sub>2</sub>) using AIRE is 3.0 AU and it is effective for the identification of a response to lactose-containing foods in individuals experiencing LM, although its upper limit is only 81 ppm. |
|
dc.format.medium |
Electronic |
|
dc.language |
eng |
|
dc.publisher |
MDPI AG |
|
dc.relation.ispartofseries |
Nutrients |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
|
dc.subject |
Humans |
|
dc.subject |
Lactose Intolerance |
|
dc.subject |
Lactose |
|
dc.subject |
Breath Tests |
|
dc.subject |
Adult |
|
dc.subject |
Female |
|
dc.subject |
Male |
|
dc.subject |
Young Adult |
|
dc.subject |
breath hydrogen |
|
dc.subject |
carbohydrate malabsorption |
|
dc.subject |
dairy |
|
dc.subject |
milk |
|
dc.subject |
personal health device |
|
dc.subject |
Adult |
|
dc.subject |
Breath Tests |
|
dc.subject |
Female |
|
dc.subject |
Humans |
|
dc.subject |
Lactose |
|
dc.subject |
Lactose Intolerance |
|
dc.subject |
Male |
|
dc.subject |
Young Adult |
|
dc.subject |
Science & Technology |
|
dc.subject |
Life Sciences & Biomedicine |
|
dc.subject |
Nutrition & Dietetics |
|
dc.subject |
carbohydrate malabsorption |
|
dc.subject |
breath hydrogen |
|
dc.subject |
personal health device |
|
dc.subject |
milk |
|
dc.subject |
dairy |
|
dc.subject |
INTOLERANCE |
|
dc.subject |
DIAGNOSIS |
|
dc.subject |
TOLERANCE |
|
dc.subject |
DIET |
|
dc.subject |
0908 Food Sciences |
|
dc.subject |
1111 Nutrition and Dietetics |
|
dc.title |
Validity of a Portable Breath Analyser (AIRE) for the Assessment of Lactose Malabsorption. |
|
dc.type |
Journal Article |
|
dc.identifier.doi |
10.3390/nu11071636 |
|
pubs.issue |
7 |
|
pubs.begin-page |
1636 |
|
pubs.volume |
11 |
|
dc.date.updated |
2021-05-03T20:49:19Z |
|
dc.rights.holder |
Copyright: The authors |
en |
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/31319625 |
|
pubs.publication-status |
Published |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
research-article |
|
pubs.subtype |
Journal Article |
|
pubs.elements-id |
777203 |
|
dc.identifier.eissn |
2072-6643 |
|
dc.identifier.pii |
nu11071636 |
|
pubs.number |
ARTN 1636 |
|
pubs.online-publication-date |
2019-7-17 |
|