Prevalence of antidepressant use and unmedicated depression in pregnant New Zealand women

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dc.contributor.author Svardal, Charlotte A
dc.contributor.author Waldie, Karen
dc.contributor.author Milne, Barry
dc.contributor.author Morton, Susan MB
dc.contributor.author D’Souza, Stephanie
dc.date.accessioned 2021-08-11T22:35:58Z
dc.date.available 2021-08-11T22:35:58Z
dc.identifier.issn 0004-8674
dc.identifier.uri https://hdl.handle.net/2292/55975
dc.description.abstract <jats:sec><jats:title>Background:</jats:title><jats:p> Throughout pregnancy, women are at an increased risk of depression, with prevalence estimates between 6.5% and 18%. Global prevalence of antenatal antidepressant use is considerably lower at 3%. </jats:p></jats:sec><jats:sec><jats:title>Objective:</jats:title><jats:p> The present study determined the proportion of women taking antidepressants across pregnancy in New Zealand. We investigated whether variation exists across age bands, area-level deprivation and ethnicities, and identified how many women experienced unmedicated depression. </jats:p></jats:sec><jats:sec><jats:title>Method:</jats:title><jats:p> Antenatal data ( n = 6822) consisted of primarily third-trimester interviews conducted with mothers participating in Growing Up in New Zealand, a longitudinal study investigating child development. Women were asked about their antidepressant intake during pregnancy and assessed on antenatal depression symptoms using the Edinburgh Postnatal Depression Scale. Antidepressant use data were also compared to population-level data from Statistics New Zealand’s Integrated Data Infrastructure. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> Antidepressant prevalence across pregnancy was 3.2%, with a 2.7% prevalence in trimester one and 2.6% following the first trimester. There was no significant difference in usage within age bands and area-level deprivation quintiles. Ethnicity-specific data revealed that Pasifika and Asian ethnicities had the lowest antidepressant use, and New Zealand Europeans the highest. The rate of unmedicated depression, where women met the Edinburgh Postnatal Depression Scale criteria for significant depressive symptoms but did not receive antidepressants during pregnancy, was 11.8%, indicating that antenatal depression treatment may be inadequate. Greater rates of unmedicated depression were seen for younger women (⩽24 years), those living in high deprivation areas and mothers of Pasifika, Asian and Māori ethnicities. </jats:p></jats:sec><jats:sec><jats:title>Conclusions:</jats:title><jats:p> Antenatal antidepressant use in New Zealand follows global prevalence estimates and highlights possible undertreatment of antenatal depression in New Zealand. Future research including other treatment types (e.g. behavioural therapy) is needed to evaluate whether undertreatment occurs across all treatment options. </jats:p></jats:sec>
dc.language en
dc.publisher SAGE Publications
dc.relation.ispartofseries Australian & New Zealand Journal of Psychiatry
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm
dc.subject 11 Medical and Health Sciences
dc.subject 17 Psychology and Cognitive Sciences
dc.title Prevalence of antidepressant use and unmedicated depression in pregnant New Zealand women
dc.type Journal Article
dc.identifier.doi 10.1177/00048674211025699
pubs.begin-page 000486742110256
dc.date.updated 2021-07-15T08:36:43Z
dc.rights.holder Copyright: The author en
pubs.end-page 000486742110256
pubs.publication-status Published online
dc.rights.accessrights http://purl.org/eprint/accessRights/RetrictedAccess en
pubs.elements-id 859371
dc.identifier.eissn 1440-1614
pubs.online-publication-date 2021-7-14


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