dc.contributor.author |
Thirayan, Varun |
|
dc.contributor.author |
Jameson, Michael Barrett |
|
dc.contributor.author |
Gregor, Reinhold Theophilus |
|
dc.coverage.spatial |
Australia |
|
dc.date.accessioned |
2022-01-10T23:39:27Z |
|
dc.date.available |
2022-01-10T23:39:27Z |
|
dc.date.issued |
2021-12 |
|
dc.identifier.issn |
1445-1433 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/57921 |
|
dc.description.abstract |
<h4>Background</h4>Radiotherapy (RT) for oropharyngeal squamous cell cancer (OPSCC) is associated with malnutrition due to treatment-related mucositis and dysphagia. While percutaneous endoscopic gastrostomy (PEG) feeding can improve nutrition, it has acute and late complications, including dependence on PEG feeding. We retrospectively evaluated patient outcomes by whether gastrostomy placement was prophylactic (P-G) or reactive to RT complications (R-G).<h4>Methods</h4>Retrospective analysis of OPSCC patients undergoing curative-intent RT at Waikato Hospital between 2010 and 2015.<h4>Results</h4>Of 103 OPSCC patients treated with RT (+/- chemotherapy) 21 had P-G, 15 had R-G and 67 had none (No-G). P-G patients were significantly more likely to be female, older, have higher tumour stage and receive bilateral RT (all p < 0.05). P-G and No-G patients had similar rates and duration of hospital admission for complications during treatment, but both were significantly less than in R-G patients (admission rates 52.3%, 49.3% and 86.7%, and mean length of stay 3.5, 3.3 and 11.9 days, respectively; p < 0.001). R-G patients also had greater RT treatment delays than P-G or No-G patients (mean 1.1, 0.7 and 0.4 days, respectively, p < 0.05). No significant differences were noted between groups in PEG dependence or weight change during, or 1, 3 or 6 months after, RT. Weight loss was not significantly different with P-G than R-G despite more frequent use of bilateral RT fields in the former group.<h4>Conclusions</h4>P-G placement affords shorter and less frequent hospital admissions than R-G during RT for OPSCC, with no increased complications or gastrostomy-dependence rates. |
|
dc.format.medium |
Print-Electronic |
|
dc.language |
eng |
|
dc.publisher |
Wiley |
|
dc.relation.ispartofseries |
ANZ journal of surgery |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.subject |
Humans |
|
dc.subject |
Head and Neck Neoplasms |
|
dc.subject |
Gastrostomy |
|
dc.subject |
Retrospective Studies |
|
dc.subject |
Female |
|
dc.subject |
Male |
|
dc.subject |
Squamous Cell Carcinoma of Head and Neck |
|
dc.subject |
Outcome Assessment, Health Care |
|
dc.subject |
enteral nutrition |
|
dc.subject |
gastrostomy |
|
dc.subject |
otolaryngology head and neck surgery |
|
dc.subject |
papillomavirus |
|
dc.subject |
radiotherapy |
|
dc.subject |
squamous cell carcinoma |
|
dc.subject |
surgical oncology |
|
dc.subject |
Science & Technology |
|
dc.subject |
Life Sciences & Biomedicine |
|
dc.subject |
Surgery |
|
dc.subject |
enteral nutrition |
|
dc.subject |
gastrostomy |
|
dc.subject |
otolaryngology head and neck surgery |
|
dc.subject |
papillomavirus |
|
dc.subject |
radiotherapy |
|
dc.subject |
squamous cell carcinoma |
|
dc.subject |
surgical oncology |
|
dc.subject |
PEG TUBE PLACEMENT |
|
dc.subject |
NECK-CANCER |
|
dc.subject |
HEAD |
|
dc.subject |
CHEMORADIOTHERAPY |
|
dc.subject |
SURVIVAL |
|
dc.subject |
OUTCOMES |
|
dc.subject |
IMPACT |
|
dc.subject |
1103 Clinical Sciences |
|
dc.title |
Prophylactic versus reactive percutaneous endoscopic gastrostomy in oropharyngeal squamous cell carcinoma patients undergoing radical radiotherapy. |
|
dc.type |
Journal Article |
|
dc.identifier.doi |
10.1111/ans.17159 |
|
pubs.issue |
12 |
|
pubs.begin-page |
2720 |
|
pubs.volume |
91 |
|
dc.date.updated |
2021-12-28T21:33:07Z |
|
dc.rights.holder |
Copyright: The author |
en |
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/34427036 |
|
pubs.end-page |
2725 |
|
pubs.publication-status |
Published |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Journal Article |
|
pubs.elements-id |
865029 |
|
dc.identifier.eissn |
1445-2197 |
|
pubs.online-publication-date |
2021-8-23 |
|