dc.contributor.author |
Liu, Gordon XH |
|
dc.contributor.author |
Harding, Jane E |
|
dc.contributor.author |
PIANO Study Team |
|
dc.coverage.spatial |
United States |
|
dc.date.accessioned |
2022-02-16T03:46:39Z |
|
dc.date.available |
2022-02-16T03:46:39Z |
|
dc.date.issued |
2021-1 |
|
dc.identifier.citation |
PloS one 16(6):e0253026 Jan 2021 |
|
dc.identifier.issn |
1932-6203 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/58212 |
|
dc.description.abstract |
<h4>Background</h4>Children born preterm, particularly at earlier gestations, are at increased risk for mortality and morbidity, but later health-related quality of life (HRQoL) is less well described. Neurodevelopmental impairment and socio-economic status may also influence HRQoL. Our aim was to describe the HRQoL of a cohort of New Zealand children born very and extremely preterm, and how this is related to neurodevelopmental impairment, gestational age, and socio-economic deprivation.<h4>Methods</h4>Children born <30 weeks' gestation or <1500 g birthweight were assessed at 7 years' corrected age. Caregivers completed the Child Health Questionnaire Parent Form (CHQ-PF50), and the Health Utilities Index Mark 2 (HUI-2). Neurodevelopmental impairment was defined as Wechsler full scale intelligence quotient below -1 standard deviation (SD), Movement Assessment Battery for Children total score ≤15 percentile, cerebral palsy, deafness, or blindness.<h4>Results</h4>Data were collected for 127 children, of whom 60 (47%) had neurodevelopmental impairment. Overall, HRQoL was good: mean (SD) CHQ-PF50 physical summary score = 50.8 (11.1), psychosocial summary score = 49.3 (9.1) [normative mean 50 (10)]; HUI-2 dead-healthy scale = 0.92 (0.09) [maximum 1.0]. Neurodevelopmental impairment, lower gestational age, and higher socio-economic deprivation were all associated with reduced HRQoL. However, on multivariable analysis, only intelligence quotient and motor function were associated with psychosocial HRQoL, while intelligence quotient was associated with physical HRQoL.<h4>Conclusions</h4>Most seven-year-old children born very and extremely preterm have good HRQoL. Further improvements will require reduced neurodevelopmental impairment. |
|
dc.format.medium |
Electronic-eCollection |
|
dc.language |
eng |
|
dc.publisher |
Public Library of Science (PLoS) |
|
dc.relation.ispartofseries |
PloS one |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
|
dc.subject |
PIANO Study Team |
|
dc.subject |
Humans |
|
dc.subject |
Infant, Premature, Diseases |
|
dc.subject |
Cohort Studies |
|
dc.subject |
Gestational Age |
|
dc.subject |
Pregnancy |
|
dc.subject |
Quality of Life |
|
dc.subject |
Child |
|
dc.subject |
Child, Preschool |
|
dc.subject |
Infant |
|
dc.subject |
Infant, Newborn |
|
dc.subject |
Caregivers |
|
dc.subject |
New Zealand |
|
dc.subject |
Female |
|
dc.subject |
Male |
|
dc.subject |
Infant, Extremely Premature |
|
dc.subject |
Caregivers |
|
dc.subject |
Child |
|
dc.subject |
Child, Preschool |
|
dc.subject |
Cohort Studies |
|
dc.subject |
Female |
|
dc.subject |
Gestational Age |
|
dc.subject |
Humans |
|
dc.subject |
Infant |
|
dc.subject |
Infant, Extremely Premature |
|
dc.subject |
Infant, Newborn |
|
dc.subject |
Infant, Premature, Diseases |
|
dc.subject |
Male |
|
dc.subject |
New Zealand |
|
dc.subject |
Pregnancy |
|
dc.subject |
Quality of Life |
|
dc.subject |
Science & Technology |
|
dc.subject |
Multidisciplinary Sciences |
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dc.subject |
Science & Technology - Other Topics |
|
dc.subject |
EMOTIONAL-PROBLEMS |
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dc.subject |
MOTOR FUNCTION |
|
dc.subject |
BIRTH |
|
dc.subject |
IMPAIRMENT |
|
dc.subject |
INFANTS |
|
dc.subject |
MODEL |
|
dc.title |
Caregiver-reported health-related quality of life of New Zealand children born very and extremely preterm. |
|
dc.type |
Journal Article |
|
dc.identifier.doi |
10.1371/journal.pone.0253026 |
|
pubs.issue |
6 |
|
pubs.begin-page |
e0253026 |
|
pubs.volume |
16 |
|
dc.date.updated |
2022-01-16T21:44:03Z |
|
dc.rights.holder |
Copyright: The author |
en |
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/34101760 |
|
pubs.publication-status |
Published |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
Research Support, Non-U.S. Gov't |
|
pubs.subtype |
research-article |
|
pubs.subtype |
Journal Article |
|
pubs.elements-id |
855490 |
|
dc.identifier.eissn |
1932-6203 |
|
dc.identifier.pii |
PONE-D-21-02888 |
|
pubs.number |
ARTN e0253026 |
|
pubs.online-publication-date |
2021-6-8 |
|