dc.contributor.author |
Tomari, Shinya |
|
dc.contributor.author |
Magin, Parker |
|
dc.contributor.author |
Lasserson, Daniel |
|
dc.contributor.author |
Quain, Debbie |
|
dc.contributor.author |
Valderas, Jose M |
|
dc.contributor.author |
Dewey, Helen M |
|
dc.contributor.author |
Barber, P Alan |
|
dc.contributor.author |
Spratt, Neil J |
|
dc.contributor.author |
Cadilhac, Dominique A |
|
dc.contributor.author |
Feigin, Valery L |
|
dc.contributor.author |
Rothwell, Peter M |
|
dc.contributor.author |
Zareie, Hossein |
|
dc.contributor.author |
Garcia-Esperon, Carlos |
|
dc.contributor.author |
Davey, Andrew |
|
dc.contributor.author |
Najib, Nashwa |
|
dc.contributor.author |
Sales, Milton |
|
dc.contributor.author |
Levi, Christopher R |
|
dc.coverage.spatial |
Switzerland |
|
dc.date.accessioned |
2022-05-04T21:44:29Z |
|
dc.date.available |
2022-05-04T21:44:29Z |
|
dc.date.issued |
2020-01 |
|
dc.identifier.citation |
(2020). Frontiers in Neurology, 11, 383-. |
|
dc.identifier.issn |
1664-2295 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/58936 |
|
dc.description.abstract |
<b>Background:</b> Transient ischemic attack (TIA) and minor stroke (TIAMS) are risk factors for stroke recurrence. Some TIAMS may be preventable by appropriate primary prevention. We aimed to recruit "possible-TIAMS" patients in the INternational comparison of Systems of care and patient outcomes In minor Stroke and TIA (INSIST) study. <b>Methods:</b> A prospective inception cohort study performed across 16 Hunter-Manning region, Australia, general practices in the catchment of one secondary-care acute neurovascular clinic. Possible-TIAMS patients were recruited from August 2012 to August 2016. We describe the baseline demographics, risk factors and pre-event medications of participating patients. <b>Results:</b> There were 613 participants (mean age; 69 ± 12 years, 335 women), and 604 (99%) were Caucasian. Hypertension was the most common risk factor (69%) followed by hyperlipidemia (52%), diabetes mellitus (17%), atrial fibrillation (AF) (17%), prior TIA (13%) or stroke (10%). Eighty-nine (36%) of the 249 participants taking antiplatelet therapy had no known history of cardiovascular morbidity. Of 102 participants with known AF, 91 (89%) had a CHA2DS2-VASc score ≥ 2 but only 47 (46%) were taking anticoagulation therapy. Among 304 participants taking an antiplatelet or anticoagulant agent, 30 (10%) had stopped taking these in the month prior to the index event. <b>Conclusion:</b> This study provides the first contemporary data on TIAMS or TIAMS-mimics in Australia. Community and health provider education is required to address the under-use of anticoagulation therapy in patients with known AF, possibly inappropriate use of antiplatelet therapy and possibly inappropriate discontinuation of antiplatelet or anticoagulation therapy. |
|
dc.format.medium |
Electronic-eCollection |
|
dc.publisher |
Frontiers Media SA |
|
dc.relation.ispartofseries |
Frontiers in neurology |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
|
dc.subject |
anticoagulation therapy |
|
dc.subject |
atrial fibrillation |
|
dc.subject |
minor stroke |
|
dc.subject |
stroke-mimic syndrome |
|
dc.subject |
transient ischemic attack |
|
dc.subject |
Cardiovascular |
|
dc.subject |
Prevention |
|
dc.subject |
Stroke |
|
dc.subject |
Clinical Research |
|
dc.subject |
Science & Technology |
|
dc.subject |
Life Sciences & Biomedicine |
|
dc.subject |
Clinical Neurology |
|
dc.subject |
Neurosciences |
|
dc.subject |
Neurosciences & Neurology |
|
dc.subject |
ANTIPLATELET THERAPY |
|
dc.subject |
ORAL ANTICOAGULANTS |
|
dc.subject |
RISK |
|
dc.subject |
OXFORDSHIRE |
|
dc.subject |
TIA |
|
dc.subject |
Peripheral Vascular Disease |
|
dc.subject |
Cardiovascular System & Cardiology |
|
dc.subject |
1103 Clinical Sciences |
|
dc.subject |
1109 Neurosciences |
|
dc.subject |
1701 Psychology |
|
dc.title |
The Characteristics of Patients With Possible Transient Ischemic Attack and Minor Stroke in the Hunter and Manning Valley Regions, Australia (the INSIST Study). |
|
dc.type |
Journal Article |
|
dc.identifier.doi |
10.3389/fneur.2020.00383 |
|
pubs.begin-page |
383 |
|
pubs.volume |
11 |
|
dc.date.updated |
2022-04-06T00:04:27Z |
|
dc.rights.holder |
Copyright: The author |
en |
dc.identifier.pmid |
32670173 (pubmed) |
|
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/32670173 |
|
pubs.publication-status |
Published |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.elements-id |
783479 |
|
pubs.org-id |
Medical and Health Sciences |
|
pubs.org-id |
School of Medicine |
|
pubs.org-id |
Medicine Department |
|
dc.identifier.eissn |
1664-2295 |
|
pubs.record-created-at-source-date |
2022-04-06 |
|
pubs.online-publication-date |
2020-05-15 |
|