dc.contributor.author |
Lin, CY |
|
dc.contributor.author |
Oakley, A |
|
dc.contributor.author |
Rademaker, M |
|
dc.contributor.author |
Hill, S |
|
dc.contributor.author |
Yung, A |
|
dc.coverage.spatial |
England |
|
dc.date.accessioned |
2022-05-08T22:11:04Z |
|
dc.date.available |
2022-05-08T22:11:04Z |
|
dc.date.issued |
2013-04 |
|
dc.identifier.citation |
(2013). British Journal of Dermatology, 168(4), 815-819. |
|
dc.identifier.issn |
0007-0963 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/59053 |
|
dc.description.abstract |
<h4>Background</h4>Melanocytic naevi have been observed to undergo morphological changes following exposure to narrowband ultraviolet (NB-UV)B radiation.<h4>Objectives</h4>To analyse changes in naevi exposed to NB-UVB in a large cohort of patients.<h4>Methods</h4>Subjects referred for phototherapy had macroscopic and dermoscopic images taken of prominent melanocytic naevi at the following time points: immediately prior to NB-UVB treatment, after 10 exposures, after 30 exposures or at the end of treatment if earlier, and 3 months after discontinuing treatment. Four dermatologists, by consensus, examined each naevus for specific clinical and dermoscopic features at each time point. The size (area) of each naevus was determined by plenimetry.<h4>Results</h4>Complete sets of images were taken for 36 out of 51 patients. The most common global dermoscopic patterns in the 440 naevi examined were reticular (50%) and globular (32%). Following NB-UVB exposure, blurring or merging of lines was observed in 45% of reticular naevi. An increase in colour intensity and in the number of dots or globules was observed in 63% of globular naevi, and 167 naevi (40%) underwent a change in size. Of these, 91/167 (54%) decreased in size, with a median area reduction of 8% (0·9-42%); while 76/167 (46%) increased in size, with a median area increase of 9% (1-76%).<h4>Conclusions</h4>Around half of naevi exposed to a course of NB-UVB treatment undergo size or morphological changes. Naevi that enlarged tended to revert to pretreatment size 3 months after discontinuation of phototherapy. |
|
dc.format.medium |
Print-Electronic |
|
dc.language |
eng |
|
dc.publisher |
Wiley |
|
dc.relation.ispartofseries |
The British journal of dermatology |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.subject |
Humans |
|
dc.subject |
Nevus, Pigmented |
|
dc.subject |
Skin Neoplasms |
|
dc.subject |
Dermoscopy |
|
dc.subject |
Treatment Outcome |
|
dc.subject |
Ultraviolet Therapy |
|
dc.subject |
Tumor Burden |
|
dc.subject |
Adolescent |
|
dc.subject |
Adult |
|
dc.subject |
Aged |
|
dc.subject |
Aged, 80 and over |
|
dc.subject |
Middle Aged |
|
dc.subject |
Child |
|
dc.subject |
Female |
|
dc.subject |
Male |
|
dc.subject |
Young Adult |
|
dc.subject |
Climate-Related Exposures and Conditions |
|
dc.subject |
1103 Clinical Sciences |
|
dc.subject |
1112 Oncology and Carcinogenesis |
|
dc.title |
Effect of narrowband ultraviolet B phototherapy on melanocytic naevi. |
|
dc.type |
Journal Article |
|
dc.identifier.doi |
10.1111/bjd.12168 |
|
pubs.issue |
4 |
|
pubs.begin-page |
815 |
|
pubs.volume |
168 |
|
dc.date.updated |
2022-04-18T21:31:46Z |
|
dc.rights.holder |
Copyright: The author |
en |
dc.identifier.pmid |
23442155 (pubmed) |
|
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/23442155 |
|
pubs.end-page |
819 |
|
pubs.publication-status |
Published |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/RestrictedAccess |
en |
pubs.subtype |
Research Support, Non-U.S. Gov't |
|
pubs.subtype |
Journal Article |
|
pubs.elements-id |
852105 |
|
pubs.org-id |
Medical and Health Sciences |
|
pubs.org-id |
School of Medicine |
|
pubs.org-id |
Medicine Department |
|
dc.identifier.eissn |
1365-2133 |
|
pubs.record-created-at-source-date |
2022-04-19 |
|
pubs.online-publication-date |
2013-02-27 |
|