Grzybowski's generalized eruptive keratoacanthoma: Remission with cyclophosphamide

Show simple item record Oakley, A Ng, S
dc.coverage.spatial Australia 2022-05-09T02:36:12Z 2022-05-09T02:36:12Z 2005-05
dc.identifier.citation (2005). Australasian Journal of Dermatology, 46(2), 118-123.
dc.identifier.issn 0004-8380
dc.description.abstract A 57-year-old woman presented with intensely pruritic generalized eruptive keratoacanthomas affecting cutaneous and mucosal surfaces (Grzybowski syndrome). She derived marginal benefit from anti-pruritic agents, acitretin and methotrexate. However, cyclophosphamide 100 mg daily for 1 month followed by 3 months at 200 mg daily resulted in remarkable improvement and eventual remission without further treatment. The disease resulted in severe ectropion of upper and lower eyelids bilaterally. Two years after the onset of her disease, the lower lid ectropions were repaired using skin grafting. There was no evidence for papillomavirus infection.
dc.format.medium Print
dc.language eng
dc.publisher Wiley
dc.relation.ispartofseries Australasian Journal of Dermatology
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.
dc.subject Lip
dc.subject Mouth Mucosa
dc.subject Humans
dc.subject Mouth Diseases
dc.subject Keratoacanthoma
dc.subject Cyclophosphamide
dc.subject Antineoplastic Agents, Alkylating
dc.subject Diagnosis, Differential
dc.subject Remission Induction
dc.subject Middle Aged
dc.subject Female
dc.subject Clinical Research
dc.subject 6.1 Pharmaceuticals
dc.subject 1103 Clinical Sciences
dc.subject 1114 Paediatrics and Reproductive Medicine
dc.title Grzybowski's generalized eruptive keratoacanthoma: Remission with cyclophosphamide
dc.type Journal Article
dc.identifier.doi 10.1111/j.1440-0960.2005.00157.x
pubs.issue 2
pubs.begin-page 118
pubs.volume 46 2022-04-18T22:53:05Z
dc.rights.holder Copyright: The author en
dc.identifier.pmid 15842409 (pubmed)
pubs.end-page 123
pubs.publication-status Published
dc.rights.accessrights en
pubs.subtype Article
pubs.elements-id 55003 Medical and Health Sciences School of Medicine Medicine Department
dc.identifier.eissn 1440-0960
dc.identifier.pii AJD157
pubs.record-created-at-source-date 2022-04-19

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