Assessing integrated biomarkers of triplefin fish Forsterygion capito inhabiting contaminated marine water - A multivariate approach.

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dc.contributor.author Montenegro, Diana
dc.contributor.author González, M Teresa
dc.contributor.author Hickey, Tony
dc.contributor.author Rahnama, Mostafa
dc.contributor.author Green, Saras
dc.contributor.author Lear, Gavin
dc.coverage.spatial England
dc.date.accessioned 2022-05-20T03:08:36Z
dc.date.available 2022-05-20T03:08:36Z
dc.date.issued 2022-02
dc.identifier.citation (2022). Chemosphere, 288(Pt 2), 132590-.
dc.identifier.issn 0045-6535
dc.identifier.uri https://hdl.handle.net/2292/59387
dc.description.abstract The presence of multiple chemicals in aquatic ecosystems makes evaluation of their real impact on the biota difficult. Integrated biomarkers are therefore needed to evaluate how these chemicals contribute to environmental degradation. The aims of the present study were to evaluate responses to and effects of marine pollution using a series of biomarkers through multivariate analyses. Transcriptional responses of cyp1a (cytochrome P450), mt (metallothionein), vtg (vitellogenin) and cyp19b (cytochrome P450 aromatase); branchial and hepatic histological alterations; and Fulton condition factors (CF) were evaluated, as well as the metals and polycyclic aromatic hydrocarbons present in Forsterygion capito in Auckland, New Zealand. Sites were selected along a contamination gradient: four highly contaminated sites and four less contaminated. Molecular responses with a higher relative expression of the mt and cyp1a genes were detected at a highly contaminated site (Panmure). Several histological lesion types were found in the livers of fish inhabiting both types of sites, but gill lesions were present primarily at highly contaminated sites. In terms of general health status, the lowest CF values were overwhelmingly found in fish from the same site (Panmure). The multivariate approach revealed that telangiectasia and hyperplasia were associated with the presence of chemicals, and these showed negative associations with the CF values, with fish from three highly contaminated sites being most affected. In conclusion, the multivariate approach helped to integrate these biological markers in this blennioid fish, thus providing a more holistic view of the complex chemical mixtures involved. Future studies should implement these analyses.
dc.format.medium Print-Electronic
dc.language eng
dc.publisher Elsevier BV
dc.relation.ispartofseries Chemosphere
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm
dc.subject Animals
dc.subject Water
dc.subject Metallothionein
dc.subject Ecosystem
dc.subject Water Pollution
dc.subject Biomarkers
dc.subject Environmental analysis
dc.subject Gene expression
dc.subject Histopathology
dc.subject Metals
dc.subject Polycyclic aromatic hydrocarbons
dc.subject Toxicology
dc.subject 14 Life Below Water
dc.subject Science & Technology
dc.subject Life Sciences & Biomedicine
dc.subject Environmental Sciences
dc.subject Environmental Sciences & Ecology
dc.subject POLYCYCLIC AROMATIC-HYDROCARBONS
dc.subject TAMAKI-ESTUARY
dc.subject HISTOPATHOLOGICAL ALTERATIONS
dc.subject BIOCHEMICAL RESPONSES
dc.subject SOLEA-SENEGALENSIS
dc.subject POLLUTANT STRESS
dc.subject METAL POLLUTION
dc.subject LIVER
dc.subject TOXICITY
dc.subject EXPRESSION
dc.title Assessing integrated biomarkers of triplefin fish Forsterygion capito inhabiting contaminated marine water - A multivariate approach.
dc.type Journal Article
dc.identifier.doi 10.1016/j.chemosphere.2021.132590
pubs.issue Pt 2
pubs.begin-page 132590
pubs.volume 288
dc.date.updated 2022-04-11T21:26:57Z
dc.rights.holder Copyright: The author en
dc.identifier.pmid 34662640 (pubmed)
pubs.author-url https://www.ncbi.nlm.nih.gov/pubmed/34662640
pubs.publication-status Published
dc.rights.accessrights http://purl.org/eprint/accessRights/RetrictedAccess en
pubs.subtype Journal Article
pubs.elements-id 872245
pubs.org-id Science
pubs.org-id Biological Sciences
pubs.org-id Science Research
pubs.org-id Maurice Wilkins Centre (2010-2014)
dc.identifier.eissn 1879-1298
dc.identifier.pii S0045-6535(21)03062-9
pubs.number 132590
pubs.record-created-at-source-date 2022-04-12


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