The global impact of SARS-CoV-2 in 181 people with cystic fibrosis.

Show simple item record

dc.contributor.author McClenaghan, Elliot
dc.contributor.author Cosgriff, Rebecca
dc.contributor.author Brownlee, Keith
dc.contributor.author Ahern, Susannah
dc.contributor.author Burgel, Pierre-Régis
dc.contributor.author Byrnes, Catherine A
dc.contributor.author Colombo, Carla
dc.contributor.author Corvol, Harriet
dc.contributor.author Cheng, Stephanie Y
dc.contributor.author Daneau, Géraldine
dc.contributor.author Elbert, Alexander
dc.contributor.author Faro, Albert
dc.contributor.author Goss, Christopher H
dc.contributor.author Gulmans, Vincent
dc.contributor.author Gutierrez, Hector
dc.contributor.author de Monestrol, Isabelle
dc.contributor.author Jung, Andreas
dc.contributor.author Justus, Lutz Nährlich
dc.contributor.author Kashirskaya, Nataliya
dc.contributor.author Marshall, Bruce C
dc.contributor.author McKone, Edward
dc.contributor.author Middleton, Peter G
dc.contributor.author Mondejar-Lopez, Pedro
dc.contributor.author Pastor-Vivero, M Dolores
dc.contributor.author Padoan, Rita
dc.contributor.author Rizvi, Samar
dc.contributor.author Ruseckaite, Rasa
dc.contributor.author Salvatore, Marco
dc.contributor.author Stephenson, Anne L
dc.contributor.author Filho, Luiz Vicente R da Silva
dc.contributor.author Melo, Joel
dc.contributor.author Zampoli, Marco
dc.contributor.author Carr, Siobhán B
dc.contributor.author Global Registry Harmonization Group
dc.coverage.spatial Netherlands
dc.date.accessioned 2022-06-13T23:22:49Z
dc.date.available 2022-06-13T23:22:49Z
dc.date.issued 2020-11-04
dc.identifier.citation (2020). Journal of Cystic Fibrosis, 19(6), 868-871.
dc.identifier.issn 1569-1993
dc.identifier.uri https://hdl.handle.net/2292/59817
dc.description.abstract With the growing SARS-CoV-2 pandemic, we need to better understand its impact in specific patient groups like those with Cystic Fibrosis (CF). We report on 181 people with CF (32 post-transplant) from 19 countries diagnosed with SARS-CoV-2 prior to 13 June 2020. Infection with SARS-CoV-2 appears to exhibit a similar spectrum of outcomes to that seen in the general population, with 11 people admitted to intensive care (7 post-transplant), and 7 deaths (3 post-transplant). A more severe clinical course may be associated with older age, CF-related diabetes, lower lung function in the year prior to infection, and having received an organ transplant. Whilst outcomes in this large cohort are better than initially feared overall, possibly due to a protective effect of the relatively younger age of the CF population compared to other chronic conditions, SARS-CoV-2 is not a benign disease for all people in this patient group.
dc.format.medium Print-Electronic
dc.language eng
dc.publisher Elsevier BV
dc.relation.ispartofseries Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm
dc.subject Global Registry Harmonization Group
dc.subject Lung
dc.subject Humans
dc.subject Cystic Fibrosis
dc.subject Tomography, X-Ray Computed
dc.subject Respiratory Function Tests
dc.subject Hospitalization
dc.subject Lung Transplantation
dc.subject Registries
dc.subject Mortality
dc.subject Risk Factors
dc.subject Age Factors
dc.subject Comorbidity
dc.subject Sex Factors
dc.subject Adult
dc.subject Aged
dc.subject Female
dc.subject Male
dc.subject Global Health
dc.subject Outcome Assessment, Health Care
dc.subject COVID-19
dc.subject SARS-CoV-2
dc.subject COVID-19 Testing
dc.subject Coronavirus
dc.subject Transplant
dc.subject Emerging Infectious Diseases
dc.subject Orphan Drug
dc.subject Clinical Research
dc.subject Rare Diseases
dc.subject Infectious Diseases
dc.subject Pneumonia & Influenza
dc.subject Prevention
dc.subject Transplantation
dc.subject Pneumonia
dc.subject 7.1 Individual care needs
dc.subject Infection
dc.subject Congenital
dc.subject Science & Technology
dc.subject Life Sciences & Biomedicine
dc.subject Respiratory System
dc.subject 1103 Clinical Sciences
dc.title The global impact of SARS-CoV-2 in 181 people with cystic fibrosis.
dc.type Journal Article
dc.identifier.doi 10.1016/j.jcf.2020.10.003
pubs.issue 6
pubs.begin-page 868
pubs.volume 19
dc.date.updated 2022-05-26T02:36:31Z
dc.rights.holder Copyright: The author en
dc.identifier.pmid 33183965 (pubmed)
pubs.author-url https://www.ncbi.nlm.nih.gov/pubmed/33183965
pubs.end-page 871
pubs.publication-status Published
dc.rights.accessrights http://purl.org/eprint/accessRights/RetrictedAccess en
pubs.subtype brief-report
pubs.subtype Journal Article
pubs.elements-id 827376
pubs.org-id Medical and Health Sciences
pubs.org-id School of Medicine
pubs.org-id Paediatrics Child & Youth Hlth
dc.identifier.eissn 1873-5010
dc.identifier.pii S1569-1993(20)30877-8
pubs.record-created-at-source-date 2022-05-26


Files in this item

Find Full text

This item appears in the following Collection(s)

Show simple item record

Share

Search ResearchSpace


Browse

Statistics