dc.contributor.author |
Taore, Aryaman |
|
dc.contributor.author |
Lobo, Gabriel |
|
dc.contributor.author |
Turnbull, Philip R |
|
dc.contributor.author |
Dakin, Steven C |
|
dc.coverage.spatial |
England |
|
dc.date.accessioned |
2022-07-26T22:09:41Z |
|
dc.date.available |
2022-07-26T22:09:41Z |
|
dc.date.issued |
2022-05-11 |
|
dc.identifier.citation |
(2022). Scientific Reports, 12(1), 7734-. |
|
dc.identifier.issn |
2045-2322 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/60561 |
|
dc.description.abstract |
We set out to develop a simple objective test of functional colour vision based on eye movements made in response to moving patterns. We exploit the finding that while the motion of a colour-defined stimulus can be cancelled by adding a low-contrast luminance-defined stimulus moving in the opposite direction, the "equivalent luminance contrast" required for such cancellation is reduced when colour vision is abnormal. We used a consumer-grade infrared eye-tracker to measure eye movements made in response to coloured patterns drifting at different speeds. An automated analysis of these movements estimated individuals' red-green equiluminant point and their equivalent luminance contrast. We tested 34 participants: 23 colour vision normal controls, 9 deuteranomalous and 2 protanomalous individuals. We obtained reliable estimates of strength of directed eye movements (i.e. combined optokinetic and voluntary tracking) for stimuli moving at 16 deg/s and could use these data to classify participants' colour vision status with a sensitivity rate of 90.9% and a specificity rate of 91.3%. We conclude that an objective test of functional colour vision combining a motion-nulling technique with an automated analysis of eye movements can diagnose and assess the severity of protanopia and deuteranopia. The test places minimal demands on patients (who simply view a series of moving patterns for less than 90 s), requires modest operator expertise, and can be run on affordable hardware. |
|
dc.format.medium |
Electronic |
|
dc.language |
eng |
|
dc.publisher |
Springer Nature |
|
dc.relation.ispartofseries |
Scientific reports |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
|
dc.subject |
Humans |
|
dc.subject |
Color Vision Defects |
|
dc.subject |
Eye Movements |
|
dc.subject |
Color Perception |
|
dc.subject |
Motion Perception |
|
dc.subject |
Contrast Sensitivity |
|
dc.subject |
Color Vision |
|
dc.subject |
Clinical Research |
|
dc.subject |
4.1 Discovery and preclinical testing of markers and technologies |
|
dc.subject |
4 Detection, screening and diagnosis |
|
dc.subject |
Eye |
|
dc.subject |
Science & Technology |
|
dc.subject |
Multidisciplinary Sciences |
|
dc.subject |
Science & Technology - Other Topics |
|
dc.subject |
VISUAL-FIELD LOSS |
|
dc.subject |
OPTOKINETIC NYSTAGMUS |
|
dc.subject |
RED-GREEN |
|
dc.subject |
GENE-THERAPY |
|
dc.subject |
MOTION |
|
dc.subject |
LUMINANCE |
|
dc.subject |
DISCRIMINATION |
|
dc.subject |
DOMINANCE |
|
dc.subject |
DIRECTION |
|
dc.subject |
CONTRAST |
|
dc.title |
Diagnosis of colour vision deficits using eye movements. |
|
dc.type |
Journal Article |
|
dc.identifier.doi |
10.1038/s41598-022-11152-5 |
|
pubs.issue |
1 |
|
pubs.begin-page |
7734 |
|
pubs.volume |
12 |
|
dc.date.updated |
2022-06-14T00:12:19Z |
|
dc.rights.holder |
Copyright: The author |
en |
dc.identifier.pmid |
35562176 (pubmed) |
|
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/35562176 |
|
pubs.publication-status |
Published |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
research-article |
|
pubs.subtype |
Journal Article |
|
pubs.elements-id |
902802 |
|
pubs.org-id |
Medical and Health Sciences |
|
pubs.org-id |
Optometry and Vision Science |
|
dc.identifier.eissn |
2045-2322 |
|
dc.identifier.pii |
10.1038/s41598-022-11152-5 |
|
pubs.number |
7734 |
|
pubs.record-created-at-source-date |
2022-06-14 |
|
pubs.online-publication-date |
2022-12 |
|