dc.contributor.author |
Imboden, Matthias |
|
dc.contributor.author |
Chen, Sophia |
|
dc.contributor.author |
Gudozhnik, Olexandr |
|
dc.contributor.author |
Pollock, Corey |
|
dc.contributor.author |
Javor, Josh |
|
dc.contributor.author |
Bishop, David |
|
dc.contributor.author |
Shea, Herbert |
|
dc.contributor.author |
Rosset, Samuel |
|
dc.coverage.spatial |
Switzerland |
|
dc.date.accessioned |
2022-09-16T03:52:56Z |
|
dc.date.available |
2022-09-16T03:52:56Z |
|
dc.date.issued |
2022-01 |
|
dc.identifier.citation |
(2022). Frontiers in Bioengineering and Biotechnology, 10, 934756-. |
|
dc.identifier.issn |
2296-4185 |
|
dc.identifier.uri |
https://hdl.handle.net/2292/61280 |
|
dc.description.abstract |
A cell culture well with integrated mechanical and optical stimulation is presented. This is achieved by combining dielectric elastomer soft actuators, also known as artificial muscles, and a varifocal micro-electromechanical mirror that couples light from an optical fiber and focuses it onto the transparent cell substrate. The device enables unprecedented control of <i>in vitro</i> cell cultures by allowing the experimenter to tune and synchronize mechanical and optical stimuli, thereby enabling new experimental assays in optogenetics, fluorescent microscopy, or laser stimulation that include dynamic mechanical strain as a controlled input parameter. |
|
dc.format.medium |
Electronic-eCollection |
|
dc.language |
eng |
|
dc.publisher |
Frontiers |
|
dc.relation.ispartofseries |
Frontiers in bioengineering and biotechnology |
|
dc.rights |
Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher. |
|
dc.rights.uri |
https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm |
|
dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
|
dc.subject |
dielectic elastomer actuator |
|
dc.subject |
mechanical stimulation |
|
dc.subject |
mechanotransduction |
|
dc.subject |
microoptoelectromechanical system |
|
dc.subject |
optical stimulation |
|
dc.subject |
optogenetics |
|
dc.subject |
soft actuator |
|
dc.subject |
Bioengineering |
|
dc.subject |
Biotechnology |
|
dc.subject |
0699 Other Biological Sciences |
|
dc.subject |
0903 Biomedical Engineering |
|
dc.subject |
1004 Medical Biotechnology |
|
dc.title |
The Integration of Optical Stimulation in a Mechanically Dynamic Cell Culture Substrate. |
|
dc.type |
Journal Article |
|
dc.identifier.doi |
10.3389/fbioe.2022.934756 |
|
pubs.begin-page |
934756 |
|
pubs.volume |
10 |
|
dc.date.updated |
2022-08-11T20:21:03Z |
|
dc.rights.holder |
Copyright: The authors |
en |
dc.identifier.pmid |
35928941 (pubmed) |
|
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/35928941 |
|
pubs.publication-status |
Published |
|
dc.rights.accessrights |
http://purl.org/eprint/accessRights/OpenAccess |
en |
pubs.subtype |
research-article |
|
pubs.subtype |
Journal Article |
|
pubs.elements-id |
914639 |
|
pubs.org-id |
Bioengineering Institute |
|
dc.identifier.eissn |
2296-4185 |
|
dc.identifier.pii |
934756 |
|
pubs.record-created-at-source-date |
2022-08-12 |
|
pubs.online-publication-date |
2022-07-19 |
|