A prospective investigation of cognitive-behavioural models of irritable bowel and chronic fatigue syndromes: implications for theory, classification and treatment

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dc.contributor.advisor Dr Rona Moss-Morris en
dc.contributor.author Spence, Meagan en
dc.date.accessioned 2007-07-03T22:42:26Z en
dc.date.available 2007-07-03T22:42:26Z en
dc.date.issued 2005 en
dc.identifier.citation Thesis (PhD--Health Psychology)--University of Auckland, 2005. en
dc.identifier.uri http://hdl.handle.net/2292/616 en
dc.description.abstract The purpose of this study was to prospectively evaluate the application of the cognitivebehavioural model to two common functional somatic syndromes: irritable bowel syndrome (IBS) and chronic fatigue syndrome (CFS). A range of predisposing, precipitating and perpetuating variables operationalised from this model were assessed in two acutely ill samples. The significance and relative importance of these variables with regard to the development of post-infectious IBS and CFS were then examined. At the same time, information was gathered to assess the appropriateness of an overall conceptualisation for the functional somatic syndromes. Similarities and differences between the two syndromes were investigated, and the impact of differing thresholds and disability criteria were compared to determine the utility of current diagnostic criteria. Patients with a positive laboratory test result for Campylobacter gastroenteritis or glandular fever were recruited through general practitioners. A total of 1018 participants completed a baseline questionnaire at the time of infection which included measures of anxiety, depression, perfectionism, somatisation, perceived stress, acute illness perceptions and illness related behaviours. Those previously diagnosed with CFS or IBS were excluded, along with participants experiencing any medical condition known to impact on fatigue levels or bowel function (n=183). Participants completed follow-up questionnaires at three (93% response rate) and six months (90% response rate) post-infection. At each point, cases of IBS and CFS were identified using published diagnostic criteria. Results indicated that a range of cognitive, behavioural, physiological and emotional variables were significantly related to the development of both IBS and CFS. Whilst there were some similarities between the two conditions, there were also some key differences. Depression and somatisation were significant predisposing variables in the development of CFS, but not IBS, for which anxiety was a key predictor. Perceived stress and the type of acute infection were more important as precipitants of IBS than CFS. Campylobacter was a significant predictor of IBS at both timepoints, whilst the presence of this illness type also strengthened the association between IBS and the psychological variables. In contrast, glandular fever was a significant predictor of CFS at three months only, and this iii association was outweighed by the inclusion of the psychological variables. With regard to perpetuating factors, negative illness perceptions at the time of acute infection were significantly related to both conditions, and all-or-nothing behaviour was also associated with IBS. When CFS and IBS cases at six month follow-up were compared, CFS cases had higher levels of disability, but not health care utilisation. Finally, when subthreshold cases of IBS and CFS were compared to their diagnosed counterparts, on the whole they did not differ with regard to the psychological risk factors, disability or health care utilisation. These results support the application of the cognitive-behavioural model to IBS and CFS as a useful explanatory tool and guide for treatment. The results provide a degree of empirical detail that has previously been lacking with regard to these models. Comparing the application of the model to two separate conditions has demonstrated subtle but important differences between the development of post-infectious IBS and CFS. These findings suggest that an overall conceptualisation for the functional somatic syndromes may not be capable of determining and addressing such differences for individual conditions. With regard to the diagnostic criteria for IBS and CFS, results suggest that the current criteria may be unnecessarily restrictive and complex. Simplification or the formalised addition of subthreshold conditions may result in more widespread usage and clinical applicability of these criteria. en
dc.format Scanned from print thesis en
dc.language.iso en en
dc.publisher ResearchSpace@Auckland en
dc.relation.ispartof PhD Thesis - University of Auckland en
dc.relation.isreferencedby UoA1596398 en
dc.rights Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. en
dc.rights.uri https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm en
dc.title A prospective investigation of cognitive-behavioural models of irritable bowel and chronic fatigue syndromes: implications for theory, classification and treatment en
dc.type Thesis en
thesis.degree.discipline Health Psychology en
thesis.degree.grantor The University of Auckland en
thesis.degree.level Doctoral en
thesis.degree.name PhD en
dc.rights.holder Copyright: The author en
pubs.local.anzsrc 17 - Psychology and Cognitive Sciences en
pubs.org-id Faculty of Science en


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