Immunization with adenoviral vectors carrying recombinant IL-12 and E7 enhanced the antitumor immunity against human papillomavirus 16-associated tumor.

Park, EK; Kim, YW; Lee, JM; NamKoong, SE; Kim, DG; Chun, HJ; Han, BD; Bae, SM; Jin, Hyun Sun; Sin, JI; Ahn, WS

dc.contributor.author	Park, EK	en
dc.contributor.author	Kim, YW	en
dc.contributor.author	Lee, JM	en
dc.contributor.author	NamKoong, SE	en
dc.contributor.author	Kim, DG	en
dc.contributor.author	Chun, HJ	en
dc.contributor.author	Han, BD	en
dc.contributor.author	Bae, SM	en
dc.contributor.author	Jin, Hyun Sun	en
dc.contributor.author	Sin, JI	en
dc.contributor.author	Ahn, WS	en
dc.coverage.spatial	Korea (South)	en
dc.date.accessioned	2011-02-03T02:22:50Z	en
dc.date.issued	2005-02	en
dc.identifier.citation	Cancer Res Treat 37(1):63-70 Feb 2005	en
dc.identifier.issn	2005-9256	en
dc.identifier.uri	http://hdl.handle.net/2292/6229	en
dc.description.abstract	Human papillomavirus (HPV) infection has a significant role in cervical carcinogenesis, and HPV oncoprotein E7 plays an important part in the formation and maintenance of cervical cancer. Interleukin-12 (IL-12) has been reported to induce a cellular immune response, and to suppress the tumor growth and the E7 production. Here we describe the use of adenoviral delivery of the HPV 16 E7 subunit (AdE7) along with adenoviral delivery of IL-12 (AdIL-12) in mice with HPV-associated tumors.	en
dc.language	eng	en
dc.relation.ispartofseries	Cancer Res Treat	en
dc.rights	Items in ResearchSpace are protected by copyright, with all rights reserved, unless otherwise indicated. Previously published items are made available in accordance with the copyright policy of the publisher.	en
dc.rights.uri	https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm	en
dc.title	Immunization with adenoviral vectors carrying recombinant IL-12 and E7 enhanced the antitumor immunity against human papillomavirus 16-associated tumor.	en
dc.type	Journal Article	en
dc.identifier.doi	10.4143/crt.2005.37.1.63	en
pubs.issue	1	en
pubs.begin-page	63	en
pubs.volume	37	en
dc.rights.holder	Copyright: 2005 Korean Cancer Association	en
dc.identifier.pmid	19956512	en
pubs.author-url	http://www.ncbi.nlm.nih.gov/pubmed/19956512	en
pubs.end-page	70	en
dc.rights.accessrights	http://purl.org/eprint/accessRights/RestrictedAccess	en
pubs.subtype	Article	en
pubs.elements-id	159680	en
dc.identifier.eissn	2005-9256	en
pubs.record-created-at-source-date	2013-06-05	en
pubs.dimensions-id	19956512	en